中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [4]
南海海洋研究所 [1]
化学研究所 [1]
水生生物研究所 [1]
采集方式
OAI收割 [6]
iSwitch采集 [1]
内容类型
期刊论文 [7]
发表日期
2020 [2]
2019 [2]
2018 [2]
2006 [1]
学科主题
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Repurposing a bacterial prolidase for organophosphorus hydrolysis: Reshaped catalytic cavity switches substrate selectivity
期刊论文
OAI收割
BIOTECHNOLOGY AND BIOENGINEERING, 2020, 卷号: 117, 期号: 9, 页码: 2694, 2702
作者:
Yang, Jian
;
Xiao, Yun-Zhu
;
Li, Ru
;
Liu, Yu
;
Long, Li-Juan
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/09/22
active-site reshaping
catalytic selectivity
enzyme promiscuity
protein engineering
substrate repositioning
Microalgal plastidial lysophosphatidic acid acyltransferase interacts with upstream glycerol-3-phosphate acyltransferase and defines its substrate selectivity via the two transmembrane domains
期刊论文
OAI收割
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2020, 卷号: 45, 页码: 11
作者:
Huang, Linfei
;
Yu, Lihua
;
Li, Zhongze
;
Li, Yanhua
;
Yoon, Kang-sup
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/05/13
Microalgae
Lysophosphatidic acid acyltransferase
Transmembrane domain
Substrate selectivity
Protein-protein interaction
Palladium-Catalyzed Propargylic [n+2] Cycloaddition: An Efficient Strategy for Construction of Benzo-Fused Medium-Sized Heterocycles
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2019, 卷号: 361, 期号: 4, 页码: 836-841
作者:
Liu, Zhen-Ting
;
Hu, Xiang-Ping
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/06/20
A regioselective palladium-catalyzed formal [n+2] cycloaddition of propargylic esters as C-2-synthons with various linker-tethered bisphenols for the construction of medium-sized heterocycles bearing an exocyclic double bond has been developed
The reaction features mild conditions and broad substrate scopes
as well as readily available substrates and catalysts
Under optimal conditions
various medium-sized heterocycles from eight to eleven-membered rings can be afforded in good to excellent yields and regioselectivities with high Z-selectivity for the exocyclic double bond
palladium
medium-sized ring
propargylic ester
bisphenol
cycloaddition
Palladium-catalyzed propargylic [n+2] cycloaddition: an efficient strategy for construction of benzo-fused medium-sized heterocycles
期刊论文
iSwitch采集
Advanced synthesis & catalysis, 2019, 卷号: 361, 期号: 4, 页码: 836-841
作者:
Liu, Zhen-Ting
;
Hu, Xiang-Ping
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/05/08
A regioselective palladium-catalyzed formal [n+2] cycloaddition of propargylic esters as c-2-synthons with various linker-tethered bisphenols for the construction of medium-sized heterocycles bearing an exocyclic double bond has been developed
The reaction features mild conditions and broad substrate scopes
As well as readily available substrates and catalysts
Under optimal conditions
Various medium-sized heterocycles from eight to eleven-membered rings can be afforded in good to excellent yields and regioselectivities with high z-selectivity for the exocyclic double bond
Palladium
Medium-sized ring
Propargylic ester
Bisphenol
Cycloaddition
Chemo-selective couplings of anilines and acroleins/enones under substrate control and condition control
期刊论文
OAI收割
CHINESE JOURNAL OF CATALYSIS, 2018, 卷号: 39, 期号: 11, 页码: 1782-1791
作者:
Zhou, Xukai
;
Li, Xingwei
;
Sun, Jiaqiong
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/06/20
Rh(III)-catalysis
Chemo-selectivity
Annulation
Substrate control
Condition control
Tuning of acyl-ACP thioesterase activity directed for tailored fatty acid synthesis
期刊论文
OAI收割
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 卷号: 102, 期号: 7, 页码: 3173-3182
作者:
Feng, Yanbin
;
Zhang, Yunxiu
;
Wang, Yayue
;
Liu, Jiao
;
Liu, Yinghui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/06/20
Acyl-acp Thioesterase
Medium-chain Fatty Acids
Fatty Acid Tailoring
Substrate Selectivity
Competitive Relationship
Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase
期刊论文
OAI收割
CURRENT PHARMACEUTICAL DESIGN, 2006, 卷号: 12, 期号: 35, 页码: 4555-4564
作者:
Lai, Luhua
;
Han, Xiaofeng
;
Chen, Hao
;
Wei, Ping
;
Huang, Changkang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/04/09
Sars 3c-like Proteinase
Quaternary Structure
Enzyme Catalytic Mechanism
Substrate Selectivity
Inhibitor Design