机构

• 上海药物研究所 [13]
• 武汉病毒研究所 [5]
• 上海营养与健康研究所 [5]
• 上海神经科学研究所 [4]
• 昆明动物研究所 [4]
• 上海生物化学与细胞生... [3]
• 更多

采集方式

• OAI收割 [46]
• iSwitch采集 [7]

内容类型

• 期刊论文 [52]
• 学位论文 [1]

发表日期

• 2026 [1]
• 2025 [2]
• 2024 [2]
• 2023 [1]
• 2022 [3]
• 2021 [1]
• 更多

学科主题

• Cell Biolo... [4]
• Biochemist... [3]
• Chemistry [3]
• Neuroscien... [3]
• Pharmacolo... [3]
• Biochemist... [1]
• 更多

筛选

浏览/检索结果: 共53条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Design, synthesis and biological evaluation of novel pyrrolo[1,2-b]pyridazin-2(1H)-ones as selective PARP1 inhibitors for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 307, 页码: 16 作者:  He, Qiaolin;  He, Jing;  Huan, Xiajuan;  Song, Shanshan;  Zhang, Xiaofei   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/04/01 PARP1 inhibitor  Subtype selectivity  Synthetic lethality  In vitro cytotoxicity   Proteogenomic Characterization Reveals Metabolic Vulnerabilities and Aberrant Phosphorylation in Colorectal Metastasis to Liver 期刊论文  OAI收割 ADVANCED SCIENCE, 2025, 页码: 17 作者:  Zhao, Wensi;  Zhao, Lei;  Lian, Yannan;  Liu, Zhiwei;  Li, Yaqi   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/12/04 biomarker  colorectal liver metastasis  phosphoproteomics  proteomic subtype  proteomics  SHMT1   Divergent activation patterns of BRS3 revealed by two Chinese herb-derived agonists 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 10, 页码: 5231-5243 作者:  Li, Jie;  Li, Changyao;  Zhou, Qingtong;  Han, Wei;  Fang, Mingzhu   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/12/04 Bombesin receptor subtype-3  Cryo-EM  Structural pharmacology  Unliganded  Chinese herb DSO-5a  Oridonin  Receptor activation  Drug discovery   Prognostic biomarker discovery based on proteome landscape of Chinese lung adenocarcinoma 期刊论文  OAI收割 CLINICAL PROTEOMICS, 2024, 卷号: 21, 期号: 1, 页码: 11 作者:  Huang, Yuqi;  Ma, Sheng;  Xu, Jun-Yu;  Qian, Kun;  Wang, Yaru   |  收藏  |  浏览/下载：88/0  |  提交时间：2024/02/19 Lung adenocarcinoma  Proteome  Benign lung disease cases  Solid pathological subtype  Prognostic biomarker   Robustly uncovering the heterogeneity of neurodegenerative disease by using data-driven subtyping in neuroimaging: A review 期刊论文  OAI收割 BRAIN RESEARCH, 2024, 卷号: 1823, 页码: 13 作者:  Chen, Pindong;  Zhang, Shirui;  Zhao, Kun;  Kang, Xiaopeng;  Rittman, Timothy   |  收藏  |  浏览/下载：57/0  |  提交时间：2024/02/22 Neurodegenerative diseases  Alzheimer's disease  Heterogeneity  Subtype  Data-driven   Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：63/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   Two subtypes of schizophrenia identified by an individual-level atypical pattern of tensor-based morphometric measurement 期刊论文  OAI收割 CEREBRAL CORTEX, 2022, 页码: 18 作者:  Shi, Weiyang;  Fan, Lingzhong;  Wang, Haiyan;  Liu, Bing;  Li, Wen   |  收藏  |  浏览/下载：95/0  |  提交时间：2022/09/19 schizophrenia  subtype  structural MRI  neuroimaging-clinic association analysis  neuroimaging-transcription association analysis   Effects of extreme temperature on the risk of preterm birth in China: A population-based multi-center cohort study 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2022, 卷号: 24, 页码: 12 作者:  Ren, Meng;  Wang, Qiong;  Zhao, Wei;  Ren, Zhoupeng;  Zhang, Huanhuan   |  收藏  |  浏览/下载：44/0  |  提交时间：2022/09/21 Extreme temperature  Climate change  Preterm birth  Clinical subtype  China   Breast Cancer Molecular Subtype Prediction on Pathological Images with Discriminative Patch Selection and Multi-Instance Learning 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 11 作者:  Liu, Hong;  Xu, Wen-Dong;  Shang, Zi-Hao;  Wang, Xiang-Dong;  Zhou, Hai-Yan   |  收藏  |  浏览/下载：60/0  |  提交时间：2022/12/07 pathological image  weakly supervised learning  molecular subtype  breast cancer  H&E   Lithium mineralization in Qomolangma: First report of elbaitelepidolite subtype pegmatite in the Himalaya leucogranite belt 期刊论文  OAI收割 ACTA PETROLOGICA SINICA, 2021, 卷号: 37, 期号: 11, 页码: 3287-U44 作者:  Liu Chen;  Wang RuCheng;  Wu FuYuan;  Xie Lei;  Liu XiaoChi   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/07/05 Himalaya  Qomolangma  Li mineralization  Elbaite-lepidolite subtype pegmatite