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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
上海神经科学研究所 [12]
上海生物化学与细胞... [12]
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期刊论文 [59]
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2023 [1]
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Neuroscien... [7]
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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:
Zhou,Gui-Feng
;
Tang,Jing
;
Ma,Yuan-Lin
;
Fu,Xian
;
Liu,Jun-Yan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/09
conophylline
ARL6IP1
5'UTR
FXR1
BACE1 translation
AMYLOID PRECURSOR PROTEIN
A-BETA
TRANSGENIC MICE
MOUSE MODEL
NEURODEGENERATION
EXPRESSION
REDUCTION
MEMBRANE
MEMORY
ER
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Altered Response to Total Body Irradiation of C57BL/6-Tg (CAG-EGFP) Mice
期刊论文
OAI收割
DOSE-RESPONSE, 2020, 卷号: 18, 期号: 3, 页码: 11
作者:
Liu, Cuihua
;
Tanaka, Kaoru
;
Katsube, Takanori
;
Vares, Guillaume
;
Maruyama, Kouichi
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/15
green fluorescent protein
apoptosis
bone marrow death
adaptive response
ionizing radiation
GFP transgenic mice
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
期刊论文
OAI收割
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:
Guo, Xiaodan
;
Lv, Jianlu
;
Lu, Jian
;
Fan, Lei
;
Huang, Xi
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Ginseng
Autophagy
BACE1
ER stress
Amyloid beta
Apoptosis
APP/PS1 transgenic mice
Impaired sperm maturation in conditional Lcn6 knockout mice
期刊论文
OAI收割
BIOLOGY OF REPRODUCTION, 2018, 卷号: 98, 期号: 1, 页码: 28-41
作者:
Yin, Qianqian
;
Shen, Jia
;
Wan, Xiaofeng
;
Liu, Qiang
;
Zhou, Yuchuan
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/04/28
Spontaneous Acrosome Reaction
Mouse Spermatozoa
Zona-pellucida
Compensatory Mechanisms
Gene-expression
Transgenic Mice
Protein 4
In-vitro
Fertilization
Calcium
Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target
期刊论文
OAI收割
CELL REPORTS, 2018, 卷号: 25, 期号: 5, 页码: 1241-+
作者:
Zhao, Huan
;
He, Lingjuan
;
Li, Yan
;
Pu, Wenjuan
;
Liu, Qiaozhen
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/04/28
Protein-coupled Receptor
In-vivo
Apelin-apj
Endothelial-cells
Angiogenic Factor
Genetic Ablation
Transgenic Mice
Toxin Gene
T-cells
Expression
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:
Li, Cong
;
Gu, Xiao-dan
;
Lei, Min
;
Wu, Jia-yi
;
Jin, Jia-zhen
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
thamnoliavermicularisextractimproveslearningabilityinappps1transgenicmicebyamelioratingbothaandtaupathologies
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 1, 页码: 9
作者:
Li Cong
;
Guo Xiaodan
;
Lei Min
;
Wu Jiayi
;
Jin Jiazhen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-β
Tau
autophagy
BACE1
GSK3β
PI_3K