中国科学院机构知识库网格系统: 检索

中国科学院机构知识库网格

Chinese Academy of Sciences Institutional Repositories Grid

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	Advancing active compound discovery for novel drug targets: insights from AI-driven approaches 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 12 作者: Wang, Xing-you; Chen, Yang; Li, Yu-fan; Wei, Chao-yang; Liu, Meng-ya \| 收藏 \| 浏览/下载：25/0 \| 提交时间：2025/08/20 AI-driven drug discovery novel drug targets molecular design ligand exploration phenotypic drug discovery undruggable targets
	Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins 期刊论文 OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17 作者: Yu, Qian; Wang, Zheng; Tu, Yutong; Cao, Yu; Zhu, Huajian \| 收藏 \| 浏览/下载：59/0 \| 提交时间：2024/05/07 20S proteasome Proteasome activation IDPs Undruggable Protein homeostasis
	The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文 OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者: Liang, Xuewu; Ren, Hairu; Han, Fengyang; Liang, Renwen; Zhao, Jiayan \| 收藏 \| 浏览/下载：73/0 \| 提交时间：2024/01/16 chimeric design degradation System PROTAC targeted degradation technology undruggable targets