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• 西北高原生物研究所 [21]
• 化学研究所 [20]
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• 2021 [4]
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筛选

浏览/检索结果: 共105条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/01/04 YL-0919  medial prefrontal cortex  GABAergic neurons  5-HT1A receptor  GAD67-GFP transgenic mice  disinhibition  fluoxetine  electrophysiological recording   Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17 作者:  Xie, Hong-Xu;  Zhang, Juan;  Li, Yue;  Zhang, Jin-He;  Liu, Shan-Kui   |  收藏  |  浏览/下载：84/0  |  提交时间：2021/11/04 Tetrahydrobenzo[b]thiophen-2-yl)urea  alpha-Glucosidase inhibitors  Non-competitive inhibitor  Molecular docking  Anti-hyperglycaemic activity  Type 2 diabetes   Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文  OAI收割 PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664 作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin   |  收藏  |  浏览/下载：57/0  |  提交时间：2021/12/01 IDH1-R132H inhibitors  synthesis  biological activity  docking  3-(indol-3-yl)-4-(pyrazolo-[3  4-c]pyridazin-3-yl)-maleimides   Discovery of 2-(5-(quinolin-6-yl)-1,3,4-oxadiazol-2-yl)acetamide derivatives as novel PI3K alpha inhibitors via docking-based virtual screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 9 作者:  Gu, Dongyan;  Cheng, Gang;  Zhang, Mengmeng;  Zhou, Yu-Bo;  Li, Jia   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/05/24 PI3K alpha inhibitors  Virtual screening  2-(5-(quinolin-6-yl)-1,3,4 oxadiazol-2-yl)acetamide  Molecular dynamics   Synthesis of oleandrin derivatives and their cytotoxic activity 期刊论文  OAI收割 STEROIDS, 2020, 卷号: 159, 页码: 7 作者:  Zhang, Yanzhi;  Chen, Xubing;  Zhou, Yang;  Hou, Jinjun;  Long, Huali   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24 Cardiac glycosides  Oleandrin (OL)  Natural product  OL-4 '-yl ester  Cytotoxicity   Using 4-(Carbazole-9-yl)-benzyl Chloroformate as a Derivatization Reagent for the Measurement of Amino Acids in Tea Samples by High-Performance Liquid Chromatography with Fluorescence Detection 期刊论文  OAI收割 CHROMATOGRAPHIA, 2020, 卷号: 83, 期号: 4 作者:  Wang, Xu;  You, Jinmao;  Sun, Zhiwei;  Ji, Zhongyin;  Zhang, Shijuan   |  收藏  |  浏览/下载：31/0  |  提交时间：2020/11/25 HPLC-FLD  LC-MS  Derivatization  4-(Carbazole-9-yl)-benzyl chloroformate (CBBC-Cl)  Amino acids   Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204 作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 type 2 diabetes mellitus  hepatic gluconeogenesis  AMPK signaling pathway  (E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)  4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)  prodrug   Rapid microwave assisted derivatization of nitrofuran metabolites for analysis in shrimp by high performance liquid chromatography-fluorescence detector 期刊论文  OAI收割 MICROCHEMICAL JOURNAL, 2019, 卷号: 150 作者:  Luo, Xianzhu;  Yu, Yanxin;  Kong, Xiaojian;  Wang, Xu;  Ji, Zhongyin   |  收藏  |  浏览/下载：77/0  |  提交时间：2019/11/26 Microwave-assisted derivatization  Nitrofurans metabolites  HPLC-FLD  4-(Acridone-10-yl)benzaldehyde  Box-Behnken design   HPLC determination of gamma-aminobutyric acid and its analogs in human serum using precolumn fluorescence labeling with 4-(carbazole-9-yl)-benzyl chloroformate 期刊论文  OAI收割 JOURNAL OF SEPARATION SCIENCE, 2019, 卷号: 42, 期号: 4 作者:  Yu, Yanxin;  You, Jinmao;  Sun, Zhiwei;  Ji, Zhongyin;  Hu, Na   |  收藏  |  浏览/下载：55/0  |  提交时间：2019/11/26 gamma-aminobutyric acid  4-(carbazole-9-yl)-benzyl chloroformate  high-performance liquid chromatography  human serum   Novel fluorescence labeling reagent 4-(carbazole-9-yl)-benzyl chloroformate and its application in the determination of nitrofuran metabolites compounds in foodstuffs by high performance liquid chromatography with fluorescence detection 期刊论文  OAI收割 MICROCHEMICAL JOURNAL, 2019, 卷号: 145 作者:  Yu, Yanxin;  Li, Ning;  Jin, Qianqian;  Ji, Zhongyin;  Sun, Zhiwei   |  收藏  |  浏览/下载：54/0  |  提交时间：2019/11/26 Nitrofurans metabolites compounds  Foodstuffs  4-(Carbazole-9-yl)-benzyl chloroformate  HPLC-FLD