中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [27]
大连化学物理研究所 [2]
武汉病毒研究所 [2]
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期刊论文 [33]
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The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:
Xu, Chi
;
Cheng, Yun
;
Han, Manman
;
Tao, Yimin
;
Liu, Jing-Gen
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/04/10
Adenosine A1 receptor
N6-cyclohexyladenosine
Delta opioid receptor
Raf-1
Desensitization
Adenosine A(1) receptors contribute to immune regulation after neonatal hypoxic ischemic brain injury
期刊论文
OAI收割
PURINERGIC SIGNALLING, 2016, 卷号: 12, 期号: 1, 页码: 89-101
作者:
Winerdal, Max
;
Winerdal, Malin E.
;
Wang, Ying-Qing
;
Fredholm, Bertil B.
;
Winqvist, Ola
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Brain hypoxic-ischemia
Neuroimmunomodulation
Neonatology
Adenosine A(1) receptor
Cellular immunity
Statistical data interpretation
Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A(1) receptor-mediated transactivation of epidermal growth factor receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 3, 页码: 298-310
作者:
Zhong, Min
;
Song, Wan-ling
;
Xu, Ye-chun
;
Ye, Yang
;
Feng, Lin-yin
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
paeoniflorin
Chinese herb
cortical neurons
oxygen-glucose deprivation
neuroprotection
adenosine A(1) receptor
EGFR
transactivation
wortmannin
U0126
DPCPX
AG1478
PP2
BiPs
Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A_1 receptor-mediated transactivation of epidermal growth factor receptor
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2015, 卷号: 36, 期号: 3, 页码: 298
作者:
Zhong Min
;
Song Wanling
;
Xu Yechun
;
Ye Yang
;
Feng Linyin
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
PROTEIN-COUPLED RECEPTORS
REPERFUSION INJURY
ISCHEMIA/REPERFUSION INJURY
CEREBRAL-ISCHEMIA
ACTIVATION
RATS
PATHWAY
CELLS
PERFORMANCE
SUPPRESSES
paeoniflorin
Chinese herb
cortical neurons
oxygen-glucose deprivation
neuroprotection
adenosine A(1) receptor
EGFR
transactivation
wortmannin
U0126
DPCPX
AG1478
PP2
BiPs
GPCR A(2A)AR Agonist Binding and Induced Conformation Changes of Functional Switches
期刊论文
OAI收割
chinese journal of chemical physics, 2014, 卷号: 27, 期号: 1, 页码: 29-38
作者:
Pang, Xue-qin
;
Liu, Jian-yong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2015/11/17
A(2A) adenosine receptor
Molecular dynamics
Adenosine
Specific binding
Conformational dynamics
Ionic lock
Rotamer toggle switch
Secondary structure
Insight into the binding mode and the structural features of the pyrimidine derivatives as human A(2A) adenosine receptor antagonists
期刊论文
OAI收割
biosystems, 2014, 卷号: 115, 期号: 1, 页码: 13-22
作者:
Zhang, Lihui
;
Liu, Tianjun
;
Wang, Xia
;
Wang, Jinan
;
Li, Guohui
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2015/11/16
Pyrimidine derivatives
Human A(2A) adenosine receptor
Molecular docking
Molecular dynamics
Thermodynamic analysis
3D-QSAR
Design, synthesis and biological evaluation of bivalent ligands against A(1)-D-1 receptor heteromers
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 3, 页码: 441-452
作者:
Shen, Jian
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
G protein-coupled receptors
adenosine
dopamine
A(1) receptor
D-1 receptor
heterodimers
bivalent ligands
radiolabeled binding assay
FRET
molecular modeling
designsynthesisandbiologicalevaluationofbivalentligandsagainsta1d1receptorheteromers
期刊论文
OAI收割
actapharmacologicasinica, 2013, 卷号: 34, 期号: 3, 页码: 441
作者:
Shen Jian
;
Lei Zhang
;
Song Wanling
;
Tao Meng
;
Xin Wang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
PROTEIN-COUPLED RECEPTOR
ANGSTROM CRYSTAL-STRUCTURE
DRUG DISCOVERY
TRIPLET PUZZLE
ADENOSINE A(1)
D-1
ANTAGONIST
PROBES
PHARMACOLOGY
HOMOLOGIES
G protein-coupled receptors
adenosine
dopamine
A(1) receptor
D-1 receptor
heterodimers
bivalent ligands
radiolabeled binding assay
FRET
molecular modeling
PRESYNAPTIC INHIBITION OF GABAERGIC SYNAPTIC TRANSMISSION BY ADENOSINE IN MOUSE HYPOTHALAMIC HYPOCRETIN NEURONS
期刊论文
OAI收割
NEUROSCIENCE, 2012, 卷号: 201, 页码: 46-56
Xia, J. X.
;
Xiong, J. X.
;
Wang, H. K.
;
Duan, S. M.
;
Ye, J. N.
;
Hu, Z. A.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2012/07/13
sleep
wakefulness
adenosine
inhibitory postsynaptic currents
hypocretin
RECEPTOR-MEDIATED MODULATION
PURKINJE-CELL SYNAPSES
NUCLEUS NEURONS
LATERAL HYPOTHALAMUS
GLUTAMATE RELEASE
OREXIN NEURONS
PARALLEL FIBER
A1 RECEPTOR
IN-VITRO
RAT
Paeoniflorin suppresses the expression of intercellular adhesion molecule-1 (ICAM-1) in endotoxin-treated human monocytic cells
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 卷号: 164, 期号: 2B, 页码: 694-703
作者:
Jin, Lei
;
Zhang, Li-Min
;
Xie, Ke-Qiang
;
Ye, Yang
;
Feng, Linyin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
PF
ICAM-1
U937 cell
adenosine A(1) receptor
NF-kappa B pathway
MAPK pathway
HUVECs