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浏览/检索结果: 共127条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin 期刊论文  OAI收割 出版物, 3111, 期号: 0, 页码: 1-62 作者:  M Iijima;  T Yoshimizu;  T Shimazaki;  K Tokugawa;  K Fukumoto   |  收藏  |  浏览/下载：639/0  |  提交时间：2017/07/24 Arginine Vasopressin  V1b Receptor Antagonist  Depression  Anxiety  Hpa Axis   Benzothiazole amide analogues as antagonists of TRPC 6 channels: A therapeutic approach for kidney fibrosis 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16 作者:  Ren, Chunlin;  Xu, Qiding;  Luo, Qiusi;  Qiao, Xue;  Ding, Taotao   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/06/23 Transient receptor potential canonical 6  channels  Antagonist  Renal fibrosis  Benzothiazole derivatives  Unilateral ureteral obstruction   Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15 作者:  Tang, Siyuan;  Hu, Shuyang;  Feng, Lijing;  Kong, Linghui;  Gui, Jiangwen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/05/27 N-Cyclopropylmethyl-nornepenthones  Structure-activity relationship  MOR antagonist  KOR agonist  Substance use disorder   The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia 期刊论文  OAI收割 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13 作者:  Cheng, Jiaxin;  Wu, Chunhui;  Wang, Yu;  Wang, Zhen;  He, Yang   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/09/24 TPN672MA  5-HT 1A receptor agonist  D 2 /D 3 receptor partial agonist  5-HT 2A receptor antagonist  Antidepressant-like  Mechanism   Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity 期刊论文  OAI收割 METHODS, 2024, 卷号: 224, 页码: 35-46 作者:  Huang, Qingsheng;  Peng, Yin;  Peng, Yuefeng;  Lin, Huijuan;  Deng, Shiqi   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/12/06 XIAP  Apoptosis  Antagonist  Smac mimetic  Caspase-3  Caspase-9   Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20 作者:  Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/06 CB2R agonist  5-HT1AR agonist  CB1R antagonist  Antidepressant  Anxiolytic   Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16 作者:  Han, Fanghui;  Zhao, Tingting;  Zhang, Yanglong;  Yun, Ying;  Xu, Yuanyuan   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/02/19 SSTR5 antagonist  Gallbladder emptying  Cholesterol gallstones   Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 11, 页码: 3916-3929 作者:  Shen, Donghang;  Li, Xin;  Guo, Shimeng;  Xie, Xin;  Nan, Fajun   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/02/27 Huntingdon's disease  G protein-coupled receptor  GPR52  alpha-methylene-gamma-butyrolactones  antagonist   Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   GPR84 regulates pulmonary inflammation by modulating neutrophil functions 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1665-1675 作者:  Wang, Si-wei;  Zhang, Qing;  Lu, Dan;  Fang, You-chen;  Yan, Xiao-ci   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/27 GPR84  acute lung injury  inflammation  neutrophil  ROS  antagonist