中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
金属研究所 [4]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2020 [1]
2016 [2]
2015 [2]
2014 [2]
2013 [5]
2012 [2]
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Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707
作者:
Liu Tongchao
;
Peng Xia
;
Ma Yuchi
;
Ji Yinchun
;
Chen Danqi
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/02/02
RECEPTOR TYROSINE KINASE
INVASIVE GROWTH
SCATTER FACTOR
CANCER
DOCKING
c-Met inhibitors
hepatocyte growth factor receptor
imidazo1,2-apyridine
anticancer agents
drug discovery
Discovery of a new series of imidazo1,2-apyridine compounds as selective c-Met inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 5, 页码: 698-707
作者:
Liu Tongchao
;
Peng Xia
;
Ma Yuchi
;
Ji Yinchun
;
Chen Danqi
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/02/02
RECEPTOR TYROSINE KINASE
INVASIVE GROWTH
SCATTER FACTOR
CANCER
DOCKING
c-Met inhibitors
hepatocyte growth factor receptor
imidazo1,2-apyridine
anticancer agents
drug discovery
Design, Synthesis, and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Derivatives as Potent c-Met Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 6, 期号: 5, 页码: 507-512
作者:
Li, Chunpu
;
Ai, Jing
;
Zhang, Dengyou
;
Peng, Xia
;
Chen, Xi
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Receptor tyrosine kinase
c-Met inhibitor
imidazo[1,2-a]pyridine
metabolic stability
Discovery of potent 1H-imidazo[4,5-b]pyridine-based c-Met kinase inhibitors via mechanism-directed structural optimization
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 3, 页码: 708-716
作者:
An, Xiao-De
;
Liu, Hongyan
;
Xu, Zhong-Liang
;
Jin, Yi
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
c-Met tyrosine kinase
Small molecule inhibitor
Imidazonaphthyridinone
Imidazopyridine
Binding mode
Pyridone-3-carboxamide
Cyclopropane-1,1-dicarboxamide
SOMCL-863, a novel, selective and orally bioavailable small-molecule c-Met inhibitor, exhibits antitumor activity both in vitro and in vivo
期刊论文
OAI收割
CANCER LETTERS, 2014, 卷号: 351, 期号: 1, 页码: 143-150
作者:
Wang, Lu
;
Ai, Jing
;
Shen, Yanyan
;
Zhang, Haotian
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
c-Met
SOMCL-863
Receptor tyrosine kinase
Cancer
Angiogenesis
Yhhu3813 is a novel selective inhibitor of c-Met kinase that inhibits c-Met-dependent neoplastic phenotypes of human cancer cells
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 1, 页码: 89-97
作者:
He, Chang-xi
;
Ai, Jing
;
Xing, Wei-qiang
;
Chen, Yi
;
Zhang, Hao-tian
  |  
收藏
  |  
浏览/下载:149/0
  |  
提交时间:2019/01/08
human cancer
anticancer drug
Yhhu3813
c-Met
receptor tyrosine kinase
xenograft nude mouse model
Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1475-1483
作者:
Yu, Zhe
;
Ma, Yu-chi
;
Ai, Jing
;
Chen, Dan-qi
;
Zhao, Dong-mei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
receptor tyrosine kinase
type I c-Met inhibitor
cancer
quantum chemistry
protein-ligand interaction
symmetry-adapted perturbation theory (SAPT)
Synthesis and biological evaluation of 2-amino-5-aryl-3-benzylthiopyridine scaffold based potent c-Met inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 21, 页码: 6804-6820
作者:
Zhang, Dengyou
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Receptor tyrosine kinase
c-Met
2-Amino-5-aryl-3-benzylthiopyridine
Novel 5-(benzyloxy)pyridin-2(1H)-one derivatives as potent c-Met inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 8, 页码: 2408-2413
作者:
Zhang, Dengyou
;
Ai, Jing
;
Liang, Zhongjie
;
Zhu, Wei
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
c-Met
EBC-1 cell
Tyrosine kinase receptor