中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
过程工程研究所 [6]
上海神经科学研究所 [4]
大连化学物理研究所 [4]
长春应用化学研究所 [4]
上海生物化学与细胞生... [3]
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iSwitch采集 [2]
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期刊论文 [34]
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Discovery of novel small molecules targeting hepatitis B virus core protein from marine natural products with HiBiT-based high-throughput screening
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4914-4933
作者:
Huang, Chao
;
Jin, Yang
;
Fu, Panpan
;
Hu, Kongying
;
Wang, Mengxue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/01/06
Anti-HBV
HBV core protein
Core protein assembly modulators
Marine natural products
HiBiT
Lead compound
Naamidine J derivative
Bioactivity-driven synthesis
A Computational and Chemical Design Strategy for Manipulating Glycan-Protein Recognition
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Zhu, Qiang
;
Geng, Didi
;
Li, Jingchao
;
Zhang, Jinqiu
;
Sun, Haofan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/05/22
CH-pi interaction
glycan-protein recognition
glycoproteomics
PhoSL
core fucose
Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
期刊论文
OAI收割
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
作者:
Zhang, Bingyang
;
Yin, Shuang
;
Wang, Yingli
;
Su, Zhiguo
;
Bi, Jingxiu
  |  
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2021/08/31
hepatitis B core
molecular dynamic simulation
protein characterization
protein purification
virus‐
like particle
A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling
期刊论文
OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
作者:
Ji, Mei
;
Zhu, Jie
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Wang, Bin
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/10/30
Hepatitis b Core Protein
Virus-like Particle (Vlp)
Personalized Cancer Vaccine
Spycatcher/spytag
t Cell Epitope
Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2019, 卷号: 5, 期号: 5, 页码: 713-724
作者:
Yang, Li
;
Liu, Feifei
;
Tong, Xiankun
;
Hoffmann, Daniel
;
Zuo, Jianping
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
hepatitis B virus
HBV core protein
HBcAg
capsid assembly
capsid assembly modulators (CAMs)
antiviral therapy
clinical trials
A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 71-79
作者:
Li, Zhengjun
;
Wei, Jiangxue
;
Yang, Yanli
;
Liu, Lili
;
Ma, Guanghui
  |  
收藏
  |  
浏览/下载:283/0
  |  
提交时间:2019/04/03
Hepatitis b Core Protein
Thermal Stability
Particles
Purification
Host Cell Protein
Chromatography
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia
期刊论文
OAI收割
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
作者:
Ji, Mei
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Yu, Xiao-lin
;
Zhang, Yue
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2018/07/17
Alzheimer's Disease
Frontotemporal Dementia
Hepatitis b Core Protein
Truncated Tau
Neurofibrillary Tangles
Virus-like Particles (Vlps)
Vaccine
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia
期刊论文
OAI收割
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
作者:
Ji, M
;
Xie, XX
;
Liu, DQ
;
Yu, XL
;
Zhang, Y
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2018/12/29
Alzheimer's Disease
Virus-like Particles
Frontotemporal Dementia
In-vivo
Hepatitis b Core Protein
Neurofibrillary Degeneration
Truncated Tau
Corticobasal Degeneration
Neurofibrillary Tangles
Structural Determinants
Virus-like Particles (Vlps)
Truncated Tau
Vaccine
Immunotherapy
Protein
Pathology
Tauopathy
Small Molecule Inhibitors of Hepatitis B Virus Nucleocapsid Assembly: A New Approach to Treat Chronic HBV Infection
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2018, 卷号: 25, 期号: 7, 页码: 802-813
作者:
Yang, Li
;
Lu, Mengji
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Hepatitis B virus
core protein
capsid assembly
capsid assembly modulator
misassembly
antiviral therapy
Reaction inside a viral protein nanocage: mineralization on a nanoparticle seed after encapsulation via self-assembly
期刊论文
iSwitch采集
Nano research, 2017, 卷号: 10, 期号: 10, 页码: 3285-3294
作者:
Zhang, Wenjing
;
Zhang, Zhi-Ping
;
Zhang, Xian-En
;
Li, Feng
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/05/08
Protein nanocages
Mineralization
Gold nanoparticles
Gold-silver core-shell nanoparticles
Self-assembly