机构

• 上海药物研究所 [13]
• 长春应用化学研究所 [9]
• 上海生物化学与细胞生... [7]
• 水生生物研究所 [5]
• 上海神经科学研究所 [4]
• 海洋研究所 [4]
• 更多

采集方式

• OAI收割 [53]
• iSwitch采集 [3]

内容类型

• 期刊论文 [52]
• 学位论文 [3]
• CNKI期刊论文 [1]

发表日期

• 2024 [3]
• 2023 [1]
• 2022 [1]
• 2020 [2]
• 2019 [1]
• 2018 [1]
• 更多

学科主题

• Biochemist... [3]
• Plant Scie... [3]
• Biochemist... [2]
• Biochemist... [2]
• Neuroscien... [2]
• Cell Biolo... [1]
• 更多

筛选

浏览/检索结果: 共56条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16 作者:  Nie, Hui-Jun;  Li, Ben-Fu;  Sun, Jingya;  Yuan, Yali;  Zhang, Zhi-Gao   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/11/26 Triple-negative breast cancer  Targeting transcription regulation  Orally bioavailable degrader  PROTAC  Cyclin-dependent Kinase 9   Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 148, 页码: 15 作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Wu, Jianbo;  Zhang, Ying   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/09/26 Cyclin-dependent kinase 7  Small molecular inhibitor  Triple negative breast cancer  Thieno[3,2-d]pyrimidine derivative   Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21 作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/01/26 Thieno[3  d ]pyrimidine derivative  Cyclin-dependent kinase 7  Small molecule inhibitor  Kinome selectivity  Triple negative breast cancer   Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2023, 页码: 10 作者:  Lin, Rongkun;  Yang, Jie;  Liu, Ting;  Wang, Mingyu;  Ke, Chongrong   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 CDK9  cyclin T1  degrader  hydrophobic tag  protein degradation   Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1 期刊论文  OAI收割 FASEB JOURNAL, 2022, 卷号: 36, 期号: 5, 页码: 21 作者:  Zhu, Mengying;  Wang, Hui;  Ding, Yiluan;  Yang, Yuanyuan;  Xu, Zhuo   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15 COH29  cyclin D1  deubiquitinase  inhibitor  USP2   Sexual cell cycle initiation is regulated by CDK19 and CYC9 in Tetrahymena thermophila 期刊论文  OAI收割 JOURNAL OF CELL SCIENCE, 2020, 卷号: 133, 期号: 6, 页码: 12 作者:  Maa, Yang;  Yen, Guanxiong;  Han, Xiaojie;  Zhang, Jing;  Xiong, Jie   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/07/02 Cell cycle  Cyclin  Cyclin-dependent kinase  Sexual reproduction  Tetrahymena thermophila   Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma 期刊论文  OAI收割 JOURNAL OF CANCER, 2020, 卷号: 11 作者:  Zhu, Guanxia;  Li, Xia;  Li, Jiong;  Zhou, Wei;  Chen, Zhongjian   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/11/30 esophageal squamous cell carcinoma  oral squamous cell carcinoma  arsenic trioxide  cyclin D1  PD-L1  CDK4/6   Aminocyclopropane-1-carboxylic acid is a key regulator of guard mother cell terminal division in Arabidopsis thaliana 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL BOTANY, 2019, 卷号: 70, 期号: 3, 页码: 897-907 作者:  Yin, Jiao;  Zhang, Xiaoqian;  Zhang, Gensong;  Wen, Yuanyuan;  Liang, Gang   |  收藏  |  浏览/下载：85/0  |  提交时间：2019/04/22 Cyclin-dependent Kinase  Receptor Gene Family  Stomatal Development  Transcription Factor  Ethylene  Lineage  Protein  Differentiation  Proliferation  Responses   A2-type cyclin is required for the asymmetric entry division in rice stomatal development 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL BOTANY, 2018, 卷号: 69, 期号: 15, 页码: 3587-3599 作者:  Qu, Xiaoxiao;  Yan, Min;  Zou, Junjie;  Jiang, Min;  Yang, Kezhen   |  收藏  |  浏览/下载：16/0  |  提交时间：2022/02/25 Cyclin-dependent kinases  cell differentiation  cell division  guard mother cells  cyclin  rice  stomata   Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5332-5336 作者:  Fu, Yan;  Tang, Shuai;  Su, Yi;  Lan, Xiaojing;  Ye, Yan   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Cyclin-dependent kinase  CDK inhibitor  Structure-activity relationship  In vitro and in vivo profiling