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	The Development of Protein Chips for High Throughput Screening (HTS) of Chemically Labeling Small Molecular Drugs 期刊论文 OAI收割 MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2016, 卷号: 16, 期号: 10, 页码: 846-850 作者: Feng, YZ; Wang, BC; Chu, XX; Wang, YZ; Zhu, LC 收藏 \| 浏览/下载：48/0 \| 提交时间：2017/03/02 C-H activation detecting sensitivity human multi-trans membrane protein native conformation small drugs Virion-chip
	Study on sensing properties of a temperature-independent high pressure sensor base on tapered FBG (EI CONFERENCE) 会议论文 OAI收割 International Symposium on Photonics and Optoelectronics, SOPO 2010, June 19, 2010 - June 21, 2010, Chengdu, China 作者: Liu Y.; Zhang Y.; Zhang X.; Zhang X.; Zhang X. 收藏 \| 浏览/下载：26/0 \| 提交时间：2013/03/25 The sensing properties with strain and temperature of tapered FBG had been researched both theoretically and experimentally. Based on tapered FBG and thin-wall strain cylinder structure a novel temperature-independent high pressure sensor was fabricated and investigated. The tapered FBG performed as a chirped grating whose bandwidth and reflection power broadened and increased when the pressure applied on it. Moreover the bandwidth and the reflection power were temperature-independent. So the value of the strain can be obtained by detecting the reflection power. This method effectively solved the cross-sensitivity problem. The experiment results indicated that this sensor provided a measurement range of 040MPa with a sensitivity of 0.04w/MPa low cost and good application prospect. 2010 IEEE.
	A sensitive solid-phase time-resolved fluorescence immunoassay apparatus (EI CONFERENCE) 会议论文 OAI收割 International Symposium on Photoelectronic Detection and Imaging 2009: Laser Sensing and Imaging, June 17, 2009 - June 19, 2009, Beijing, China 作者: Song K.-F.; Li J.-L.; Zhang W.-L.; Wang Y.-L. 收藏 \| 浏览/下载：42/0 \| 提交时间：2013/03/25 In the device a He-Ne laser of flash frequency 1-20 Hz was adopted as exciting light source and three key technical problems have been solved successfully in order to enhance the detecting sensitivity and measuring stability of the device for time-resolved fluorimmunoassays(TRFIA) [1]. The first one is to design optimum exciting optical system so that the exciting light beam excite the sample most effectively. The second one is to have a project spectrum filter which can reduce the affection of the background light to the photomultiplier tube and also ensure influence of the stray light and mixed diffusion light to the sample fluorescence to the least the sample fluorescence through the integrating sphere and come to the grating monochromator The right wavelength will be chosed through changing the angle of incidence of the grating monochromator. The third one is to simulate the principle of sample averaging of BOXCAR averager. In the device SCM was used as primary controller and CPLD was used as timing controller. Through the preparation process signal-to-noise ratio(SNR) will be improved also adjust delay time ampling frequency and sampling number arbitrarily. By testing the sensitivity is 10-12mol/L(substance marked by Eu3+) examination repeat is &le2.5% examination linearity is from 10 -8mol/L to 10-12mol/L correlation coefficient is 99.98%(p&le0.01). The instrument is advanced for ultrasensitive detection of antigen and antibody and solve the tumor genetic variation the virus protein detection. 2009 SPIE.