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浏览/检索结果: 共855条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19 作者:  Wang, Li;  Huan, Xia-Juan;  Song, Shan-Shan;  Bao, Xu-Bin;  Tian, Chang-Qing   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/06/23 UBE4B  BET inhibitors  Resistance  KLHL22  JAK2   Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17 作者:  Jiang, Zhiyang;  Wang, Na;  Chen, Jinxiu;  Xu, Huan;  Zhu, Wenya   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/05/27 Trehalose-6-phosphate synthase  Structural optimization  Isopropanolamine compounds  Inhibitors  Fungicide candidates   Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14 作者:  Wu, Xinyuan;  Li, Shunyao;  Liang, Ting;  Yu, Qing;  Zhang, Yiwei   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/06/23 Activity-based protein profiling data  Covalent DNA-encoded chemical library  Covalent ligand selection  Lysine-targeting covalent inhibitors   Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease 期刊论文  OAI收割 ADVANCED SCIENCE, 2025, 页码: 13 作者:  Su, Haixia;  Wu, Guoqing;  Xiong, Muya;  Wang, Yuhang;  Cao, Junyuan   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/05/27 covalent inhibitors  I7L protease  monkeypox virus  protein structures  substrate proteolysis   Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives 期刊论文  OAI收割 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2025, 页码: 10 作者:  Zhang, Chun;  Yang, Yuting;  Gao, Li-Xin;  Gan, Suya;  Li, Jia   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/05/27 Fluorescent inhibitors  SHP2  2-quinolone derivatives  optical properties  drug tracing  medical diagnosis   A patenting perspective of fat mass and obesity associated protein (FTO) inhibitors: 2017-present 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 10 作者:  Dong, Ze;  Huang, Yue;  Xia, Wenyang;  Liao, Yonggang;  Yang, Cai-Guang   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/05/27 RNA methylation  FTO inhibitors  anticancer  patents  obesity   Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Geriatric Nutritional Risk Index is an effective prognostic predictor for metastatic/recurrent or unresectable esophageal cancer receiving immunotherapy 期刊论文  OAI收割 JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2025, 卷号: 16, 期号: 1, 页码: 22 作者:  Wang, Bei;  Wang, Zixuan;  Xu, Chuanhai;  Wang, Yueqin;  Gao, Honglan   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/05/27 Geriatric Nutritional Risk Index (GNRI)  esophageal squamous cell carcinoma (ESCC)  immune checkpoint inhibitors (ICIs)  programmed cell death ligand 1 (PD-L1)   Discovery of novel biaryl urea derivatives against IL-1/3 release with low toxicity based on NEK7 inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 12 作者:  Wang, Leibo;  Zhu, Kehan;  Tian, Ziyang;  Wang, Haoyu;  Jia, Yulei   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/01/14 NLRP3 inflammasome  NEK7  NLRP3-NEK7  Inhibitors