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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [2]
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OAI收割 [7]
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期刊论文 [7]
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Pharmacolo... [2]
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Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Enhanced interaction between SEC2 mutant and TCR V induces MHC II-independent activation of T cells via PKC/NF-B and IL-2R/STAT5 signaling pathways
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 51, 页码: 19771-19784
作者:
Fu, Xuanhe
;
Xu, Mingkai
;
Song, Yubo
;
Li, Yongqiang
;
Zhang, Huiwen
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2019/06/04
interleukin
NF-B (NF-KB)
STAT transcription factor
signaling
signal transduction
IL-2
staphylococcal enterotoxin C2
superantigen
T-cell receptor
T-cell activation
Interleukin-2 expression and glioma cell proliferation following Vaccinia vector gene transfection in vivo
期刊论文
OAI收割
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 4, 页码: 415-417
作者:
Wang Xiaogang
;
Wei Xuezhong
;
Liu Jiangqiu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/02/26
MURINE MODEL
IL-2
THERAPY
RESPONSES
ANTIGEN
CANCER
IMMUNITY
HEAD
Vaccinia virus vector
glioma cell
proliferation potential
in vitro
interleukin-2
Interleukin-2 regulates membrane potentials and calcium channels via mu opioid receptors in rat dorsal root ganglion neurons
期刊论文
OAI收割
NEUROPHARMACOLOGY, 2002, 卷号: 43, 期号: 8, 页码: 1324-1329
Song, P
;
Lie-Cheng, W
;
Wang, GD
;
Zhou, Z
;
Zhao, ZQ
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2012/07/23
Ca2+ current
[Ca2+]i
dorsal root ganglion
interleukin-2
intracellular recording
whole-cell patch clamp
SENSORY NEURONS
HIGH-THRESHOLD
CA2+ CURRENTS
SPINAL-CORD
RELEASE
CELLS
CA-2+
ANTINOCICEPTION
MODULATION
IL-2
Induction of Ref-1 ensures AP-1 activation in intracellular oxidative environment of IL-2-stimulated BA/F3 beta cells
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 卷号: 278, 期号: 2, 页码: 462-469
作者:
Yan, MD
;
Xu, WJ
;
Lu, LR
;
Sun, LY
;
Liu, XY
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/07/22
interleukin-2 (IL-2)
redox factor-1 (Ref-1)
activator protein-1 (AP-1)
intracellular environment
redox regulation
Molecular modeling on some human interleukins sharing gamma c of interleukin-2 receptor, and structure-function relationships
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 2000, 卷号: 532, 期号: X, 页码: 1-10
作者:
Yang J
;
Liu CQ[*]
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2010/08/24
interleukin
molecular modeling
sharing the common gamma chain of IL-2R
interaction