中国科学院机构知识库网格系统: 检索

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	Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis 期刊论文 OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 1943-1962 作者: Wang, Qi; Tang, Bixi; Sun, Dandan; Dong, Ying; Ji, Yinchun \| 收藏 \| 浏览/下载：36/0 \| 提交时间：2022/08/16 Idiopathic pulmonary fibrosis Discoidin domain receptor Kinase Inhibitor Docking
	Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation 期刊论文 OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 11, 页码: 5220-5236 作者: Guo, Ren; Jia, Xiaohui; Ding, Zhenbin; Wang, Gang; Jiang, Mengmeng \| 收藏 \| 浏览/下载：59/0 \| 提交时间：2022/08/30 Mixed lineage kinase domain-like protein MLKL liver fibrosis liver parenchymal cells hepatocyte hepatic stellate cells necroptosis
	PKZ, a Fish-Unique eIF2 alpha Kinase Involved in Innate Immune Response 期刊论文 OAI收割 FRONTIERS IN IMMUNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 6 作者: Wu, Chuxin; Zhang, Yibing; Hu, Chengyu \| 收藏 \| 浏览/下载：26/0 \| 提交时间：2020/05/28 PKZ Z alpha domain Z-DNA kinase activity fish
	Membrane-bound TNF mediates microtubule-targeting chemotherapeutics-induced cancer cytolysis via juxtacrine inter-cancer-cell death signaling 期刊论文 OAI收割 CELL DEATH AND DIFFERENTIATION, 2020, 卷号: 27, 期号: 5, 页码: 1569-1587 作者: Zhang, Jing; Yang, Yu; Zhou, Shenao; Wu, Chenlu; Qin, Jie \| 收藏 \| 浏览/下载：53/0 \| 提交时间：2020/12/21 TUMOR-NECROSIS-FACTOR MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN FACTOR-ALPHA PROMOTER PROGRAMMED NECROSIS RECOMBINANT HUMAN L929 CELLS APOPTOSIS ACTIVATION EXPRESSION
	Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism 期刊论文 OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387 作者: Lei, Saifei; Clydesdale, Lachlan; Dai, Antao; Cai, Xiaoqing; Feng, Yang \| 收藏 \| 浏览/下载：63/0 \| 提交时间：2019/01/08 G protein-coupled receptor (GPCR) glucagon receptor structure-function cell signaling site-directed mutagenesis biased agonism GLP-1 receptor glucagon-like peptide-1 class B peptide hormone ERK kinase arrestin transmembrane domain
	Targeting HER2 Aberrations in Non-Small Cell Lung Cancer with Osimertinib 期刊论文 OAI收割 CLINICAL CANCER RESEARCH, 2018, 卷号: 24, 期号: 11, 页码: 2594-2604 作者: Liu, Shengwu; Hai, Josephine; Wang, Xiaoen; Quinn, Max M.; Gao, Peng \| 收藏 \| 浏览/下载：95/0 \| 提交时间：2019/04/28 Receptor Tyrosine Kinase Phase-ii Trial Bromodomain Inhibition Combination Therapy Acquired-resistance Domain Mutations Bet Bromodomains Breast-cancer Egfr Mutant
	Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism 期刊论文 OAI收割 BIOCHEMICAL JOURNAL, 2018, 卷号: 475, 期号: -, 页码: 2209-2224 作者: Li, PP; Xu, DQ; Ma, TQ; Wang, DY; Li, WD \| 收藏 \| 浏览/下载：33/0 \| 提交时间：2019/12/17 VI SECRETION SYSTEM DEPENDENT PROTEIN-KINASE GRAM-NEGATIVE BACTERIA MYCOBACTERIUM-TUBERCULOSIS SERINE/THREONINE KINASE CATALYTIC DOMAIN CONFORMATIONAL PLASTICITY PSEUDOMONAS-AERUGINOSA ACTIVATION MECHANISM EDWARDSIELLA-TARDA
	RIPK3/Fas-Associated Death Domain Axis Regulates Pulmonary Immunopathology to Cryptococcal Infection Independent of Necroptosis 期刊论文 OAI收割 FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8, 期号: -, 页码: 1055 作者: Fa, Zhenzong; Pan, Weihua; Liao, Wanqing; Fang, Wei; Olszewski, Michal A. \| 收藏 \| 浏览/下载：21/0 \| 提交时间：2020/12/09 Cryptococcus neoformans immune responses inflammation Fas-associated death domain receptor-interacting serine/threonine kinase 3
	RIPK3/Fas-Associated Death Domain Axis Regulates Pulmonary Immunopathology to Cryptococcal Infection Independent of Necroptosis 期刊论文 OAI收割 FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8, 期号: -, 页码: 1055 作者: Fa, Zhenzong; Pan, Weihua; Liao, Wanqing; Fang, Wei; Olszewski, Michal A. \| 收藏 \| 浏览/下载：17/0 \| 提交时间：2020/12/09 Cryptococcus neoformans immune responses inflammation Fas-associated death domain receptor-interacting serine/threonine kinase 3