机构

• 广州生物医药与健康研... [6]
• 上海药物研究所 [4]
• 力学研究所 [1]
• 青岛生物能源与过程研... [1]
• 上海生物化学与细胞生... [1]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2023 [1]
• 2022 [3]
• 2021 [1]
• 2016 [3]
• 2015 [3]
• 2013 [2]
• 更多

学科主题

• Pharmacolo... [6]
• Genetics &... [1]

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules 期刊论文  OAI收割 JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42 作者:  Liu, Xiaohong;  Zhang, Wei;  Tong, Xiaochu;  Zhong, Feisheng;  Li, Zhaojun   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 De novo molecule design  Generative models  Deep learning  Virtual screening  Compound quality control   Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文  OAI收割 BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424 作者:  Wang, Jin;  Xie, Si-an;  Li, Ning;  Zhang, Tao;  Yao, Weijuan   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/10 Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction   Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 1943-1962 作者:  Wang, Qi;  Tang, Bixi;  Sun, Dandan;  Dong, Ying;  Ji, Yinchun   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/08/16 Idiopathic pulmonary fibrosis  Discoidin domain receptor  Kinase  Inhibitor  Docking   Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 1, 页码: 103-119 作者:  Tan, Xiaoqin;  Li, Chunpu;  Yang, Ruirui;  Zhao, Sen;  Li, Fei   |  收藏  |  浏览/下载：32/0  |  提交时间：2022/06/15 DrugSpaceX: a large screenable and synthetically tractable database extending drug space 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: D1, 页码: D1170-D1178 作者:  Yang, Tianbiao;  Li, Zhaojun;  Chen, Yingjia;  Feng, Dan;  Wang, Guangchao   |  收藏  |  浏览/下载：46/0  |  提交时间：2021/05/24 Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 9, 页码: 4343-4355 作者:  An, Bo;  Abbonante, Vittorio;  Xu, Huifang;  Gavriilidou, Despoina;  Yoshizumi, Ayumi 收藏  |  浏览/下载：92/0  |  提交时间：2016/05/11 Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5911-5916 Wang, Zhen; Bian, Huan; Bartual, Sergio G.; Du, Wenting; Luo, Jinfeng; Zhao, Hu; Zhang, Shasha; Mo, Cheng; Zhou, Yang; Xu, Yong; Tu, Zhengchao; Ren, Xiaomei; Lu, Xiaoyun; Brekken, Rolf A.; Yao, Libo; Bullock, Alex N.; Su, Jin; Ding, Ke 收藏  |  浏览/下载：50/0  |  提交时间：2016/12/16 Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5911-5916 作者:  Yao, Libo;  Ding, Ke;  Su, Jin;  Bullock, Alex N.;  Brekken, Rolf A.   |  收藏  |  浏览/下载：32/0  |  提交时间：2018/12/13 Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical Applications 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 8, 页码: 3287-3301 作者:  Li, Yupeng;  Lu, Xiaoyun;  Ren, Xiaomei;  Ding, Ke   |  收藏  |  浏览/下载：15/0  |  提交时间：2018/12/13 Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical Applications 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 8, 页码: 3287-3301 Li, Yupeng; Lu, Xiaoyun; Ren, Xiaomei; Ding, Ke 收藏  |  浏览/下载：25/0  |  提交时间：2016/12/16