中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [2]
寒区旱区环境与工程研... [1]
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OAI收割 [2]
iSwitch采集 [1]
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期刊论文 [3]
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2021 [1]
2020 [1]
2007 [1]
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Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1)
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:
Yu Lijie
;
Feng Bo
;
Wang Zhijia
;
Gao Lixin
;
Zhang Chun
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/11/04
5-phenyl-1,3,4-thiadiazole derivatives
Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)
inhibitors
structure-activity relationships
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Effects of freezing on plasma membrane H+-ATPase of the callus from Chorispora bungeana
期刊论文
iSwitch采集
BIOLOGIA PLANTARUM, 2007, 卷号: 51, 期号: 2, 页码: 229-234
作者:
Wu, J. M.
;
Zhao, Z. G.
;
Xing, H.
;
Guo, H. P.
;
Li, W. X.
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/10/08
alpine plant
kinase domain
p-nitrophenyl phosphate
phosphatase domain