中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
采集方式
OAI收割 [3]
内容类型
期刊论文 [3]
发表日期
2020 [2]
2019 [1]
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Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:
Zhu, Kongkai
;
Du, Daohai
;
Yang, Rui
;
Tao, Hongrui
;
Zhang, Hua
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
polycomb repressive complex 2
EZH2-EED interaction inhibitor
virtual screening
molecular dynamics simulation
c10orf12modulatesprc2histonemethyltransferaseactivityandh3k27me3levels
期刊论文
OAI收割
actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1457
作者:
Shi Yi
;
Ma Honglei
;
Zhuang Youwen
;
Wang Xiaoxi
;
Jiang Yi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
REPRESSIVE COMPLEX 2
GENOMIC TARGETS
POLYCOMB
PROTEIN
CHROMATIN
RECRUITMENT
JARID2
DIFFERENTIATION
BINDING
METHYLATION
PRC2
C10ORF12
H3K27me3
histone methyltransferase
epigenetic regulation
histone modification