机构

• 上海药物研究所 [18]
• 动物研究所 [2]
• 上海营养与健康研究所 [2]
• 生态环境研究中心 [2]
• 华南植物园 [2]
• 合肥物质科学研究院 [2]
• 更多

采集方式

• OAI收割 [32]
• iSwitch采集 [1]

内容类型

• 期刊论文 [30]
• 会议论文 [2]
• 学位论文 [1]

发表日期

• 2023 [1]
• 2022 [2]
• 2021 [1]
• 2020 [4]
• 2019 [5]
• 2018 [4]
• 更多

学科主题

• Evolutiona... [1]
• Oncology [1]
• Plant Scie... [1]
• Science & ... [1]
• 生物工程 [1]

筛选

浏览/检索结果: 共33条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644 作者:  Zhang, Yi;  Yang, Hong;  Li, Bingbing;  Li, Jiayi;  Li, Huaxuan   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency 期刊论文  OAI收割 CELL REPORTS, 2022, 卷号: 39, 期号: 10, 页码: 110928 作者:  Huang, Xin;  Bashkenova, Nazym;  Hong, Yantao;  Lyu, Cong;  Guallar, Diana   |  收藏  |  浏览/下载：12/0  |  提交时间：2022/11/08 LONG NONCODING RNA  TET PROTEINS  ENHANCER ACTIVITY  CHROMATIN  BINDING  METHYLATION  PHASE  PLURIPOTENCY  PARASPECKLES  RECRUITMENT   Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文  OAI收割 LEUKEMIA, 2022 作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng   |  收藏  |  浏览/下载：68/0  |  提交时间：2022/02/14 Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207 作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens   |  收藏  |  浏览/下载：84/0  |  提交时间：2021/08/17 SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways 期刊论文  OAI收割 CANCER CELL, 2020, 卷号: 38, 期号: 3, 页码: 350-+ 作者:  Yuan, Huairui;  Han, Ying;  Wang, Xuege;  Li, Ni;  Liu, Qiuli   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24 Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27 作者:  Zhou, Yan;  Du, Dao-Hai   |  收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 embryonic ectoderm development  Enhancer of zeste homolog 2  fluorescence polarization  high-throughput screening  homogenous time-resolved fluorescence  inhibitor  polycomb repressive complex 2   Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63 作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 polycomb repressive complex 2  EZH2-EED interaction inhibitor  virtual screening  molecular dynamics simulation   PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1 作者:  Meng Tie-Gang;  Zhou Qian;  Ma Xue-Shan;  Liu Xiao-Yu;  Meng Qing-Ren   |  收藏  |  浏览/下载：34/0  |  提交时间：2021/10/26 Targeting epigenetic machinery: Emerging novel allosteric inhibitors 期刊论文  OAI收割 PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24 作者:  Ye, Fei;  Huang, Jing;  Wang, Hongbo;  Luo, Cheng;  Zhao, Kehao   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Epigenetics  PRC2  MLL complex  SWI/SNF  DNMT1  allosteric inhibitors   AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595 作者:  Zhang, Kai-li;  Shen, Qian-qian;  Fang, Yan-fen;  Sun, Yi-ming;  Ding, Jian   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 PRC2  EZH2-EED  AZD9291  miR-34a  non-canonical base pairing