中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [11]
上海神经科学研究所 [8]
水生生物研究所 [3]
金属研究所 [2]
上海营养与健康研究所 [2]
沈阳应用生态研究所 [2]
更多
采集方式
OAI收割 [35]
iSwitch采集 [1]
内容类型
期刊论文 [36]
发表日期
2022 [2]
2020 [1]
2019 [1]
2018 [4]
2017 [4]
2014 [3]
更多
学科主题
Cell Biolo... [3]
Neuroscien... [3]
Biochemist... [2]
Biotechnol... [2]
Chemistry [2]
Pharmacolo... [2]
更多
筛选
浏览/检索结果:
共36条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
Evolution of the CBL and CIPK gene families in Medicago: genome-wide characterization, pervasive duplication, and expression pattern under salt and drought stress
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2022, 卷号: 22, 期号: 1
作者:
Zhang, Xiao-Xia
;
Ren, Xiao-Long
;
Qi, Xiao-Tong
;
Yang, Zhi-Min
;
Feng, Xiao-Lei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/07
Calcineurin B-like protein (CBL)
CBL-interacting protein kinase (CIPK)
Gene family evolution
Duplicate genes
Stress response
Medicago
Evolutionary strategies drive a balance of the interacting gene products for the CBL and CIPK gene families
期刊论文
OAI收割
NEW PHYTOLOGIST, 2020, 卷号: 226, 期号: 5, 页码: 1506-1516
作者:
Zhang, Xiaoxia
;
Li, Xiaoxia
;
Zhao, Ran
;
Zhou, Yun
;
Jiao, Yuannian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/03/01
calcineurin B-like (CBL)
CBL-interacting protein kinase (CIPK)
gene balance hypothesis (GBH)
gene retention
whole-genome duplication (WGD)
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway
期刊论文
OAI收割
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Zhao, Yue
;
Jiang, Bo
;
Luo, Jiao
  |  
收藏
  |  
浏览/下载:134/0
  |  
提交时间:2019/08/28
bromophenol
apoptosis
autophagy
phosphoinositide 3-kinase
protein kinase B
mechanistic target of rapamycin signaling
reactive oxygen species
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
Xanthoceraside attenuates amyloid beta peptide(1-42)-induced memory impairments by reducing neuroinflammatory responses in mice
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018, 页码: 18-30
作者:
Qi, Yue
;
Ji, Xue-Fei
;
Chi, Tian-Yan
;
Liu, Peng
;
Jin, Ge
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2018/09/10
Xanthoceraside
Alzheimer's Disease
Cytokine
Nuclear Factor-kappa b
Mitogen-activated Protein Kinase
Toll-like Receptor 2
A novel psoralen derivative-MPFC enhances melanogenesis via activation of p38 MAPK and PKA signaling pathways in B16 cells
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 期号: 6, 页码: 3727-3735
作者:
Yin, L (Yin, Li)
;
Pang, GX (Pang, Guangxian)
;
Niu, C (Niu, Chao)
;
Habasi, M (Habasi, Maidina)
;
Dou, J (Dou, Jun)
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2018/05/07
Melanogenesis
4-methyl-6-phenyl-2h-furo[3
Protein Kinase a Pathway
2-g]Chromen-2-one
P38 Mitogen-activated Protein Kinase
The Murine B16 Melanoma Cell
Long non-coding RNA CUDR promotes malignant phenotypes in pancreatic ductal adenocarcinoma via activating AKT and ERK signaling pathways
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 6, 页码: 2671-2682
作者:
Liang, Xing
;
Liu, Anan
;
Chen, Danlei
;
Tang, Liang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/09
pancreatic neoplasm
long non-coding RNA cancer upregulated drug resistance
epithelial-mesenchymal transition
protein kinase B
extracellular-signal-regulated kinase
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway
期刊论文
OAI收割
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:
Zhou, Ting-Ting
;
Ma, Fei
;
Shi, Xiao-Fan
;
Xu, Xin
;
Du, Te
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Gaq signaling
hepatic gluconeogenesis
protein kinase B (AKT)
type 2 diabetes mellitus (T2DM)
Vitamin A deficiency suppresses fish immune function with differences in different intestinal segments: the role of transcriptional factor NF-kappa B and p38 mitogen-activated protein kinase signalling pathways
期刊论文
OAI收割
BRITISH JOURNAL OF NUTRITION, 2017, 卷号: 117, 期号: 1, 页码: 67-82
作者:
Zhang, Li
;
Feng, Lin
;
Jiang, Wei-Dan
;
Liu, Yang
;
Wu, Pei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/09/29
Vitamin A deficiency
Intestinal segments
Immune responses
NF-kappa B canonical signalling
p38 Mitogen-activated protein kinase
Grass carp