中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [113]
采集方式
OAI收割 [113]
内容类型
期刊论文 [113]
发表日期
2019 [113]
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发表日期:2019
专题:上海药物研究所
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Deciphering molecular mechanism behind conformational change of the Sao Paolo metallo-beta-lactamase 1 by using enhanced sampling
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2019, 页码: 12
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Pang, Laixue
;
Wang, Wei
;
Zhao, Juan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Sao paolo metallo-beta-lactamase-1
REMD simulations
normal mode analysis
principal component analysis
drug resistance of antibiotics
Common activation mechanism of class A GPCRs
期刊论文
OAI收割
ELIFE, 2019, 卷号: 8, 页码: 31
作者:
Zhou, Qingtong
;
Yang, Dehua
;
Wu, Meng
;
Guo, Yu
;
Guo, Wangjing
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2020/07/01
Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23
作者:
Zou, Yi
;
Hu, Yue
;
Ge, Shushan
;
Zheng, Yingbo
;
Li, Yuezhen
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
IDO1
Heme
T cell
Cancer immunotherapy
Virtual screening
Drug design
Molecular dynamics simulation
A complex structure of arrestin-2 bound to a G protein-coupled receptor
期刊论文
OAI收割
CELL RESEARCH, 2019, 卷号: 29, 期号: 12, 页码: 971-983
作者:
Yin, Wanchao
;
Li, Zhihai
;
Jin, Mingliang
;
Yin, Yu-Ling
;
de Waal, Parker W.
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
OAI收割
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:
Zhang, Kai-li
;
Shen, Qian-qian
;
Fang, Yan-fen
;
Sun, Yi-ming
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
PRC2
EZH2-EED
AZD9291
miR-34a
non-canonical base pairing
GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH
期刊论文
OAI收割
ONCOGENE, 2019, 卷号: 38, 期号: 46, 页码: 7133-7145
作者:
Yang, Rui
;
Liu, Na
;
Chen, Ling
;
Jiang, Yiqun
;
Shi, Ying
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Genetically Encoded Residue-Selective Photo-Crosslinker to Capture Protein-Protein Interactions in Living Cells
期刊论文
OAI收割
CHEM, 2019, 卷号: 5, 期号: 11, 页码: 2955-2968
作者:
Hu, Wei
;
Yuan, Yi
;
Wang, Cai-Hu
;
Tian, Hong-Tao
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989
作者:
Zhou, Fang
;
Ding, Kang
;
Zhou, Yiqing
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01