中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [288]
采集方式
OAI收割 [288]
内容类型
期刊论文 [286]
会议论文 [2]
发表日期
2024 [9]
2023 [23]
2022 [24]
2021 [17]
2020 [35]
2019 [12]
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Neuroscien... [3]
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Biochemist... [2]
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浏览/检索结果:
共288条,第1-10条
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专题:上海药物研究所
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Machine learning prediction for constructing a universal multidimensional information library of
Panax
saponins (ginsenosides)
期刊论文
OAI收割
FOOD CHEMISTRY, 2024, 卷号: 439, 页码: 10
作者:
Wang, Hongda
;
Zhang, Lin
;
Li, Xiaohang
;
Sun, Mengxiao
;
Jiang, Meiting
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/19
Retention time
Collision cross section
Machine learning
Multidimensional information library
Hierarchical design
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/04/09
Palladium-Catalyzed Deuteration of Arylketone Oxime Ethers
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 7
作者:
Wang, Zhen-Yu
;
Zhang, Xu
;
Chen, Wen-Qing
;
Sun, Guo-Dong
;
Wang, Xing
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/13
C-C Bond Cleavage
Deacylation
Regioselective Deuteration
Difunctionalization
Palladium Catalysis
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Development of a potent benzonitrile-based inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with antitumor efficacy
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 3
作者:
Yu, Lei
;
Zhao, Pengcheng
;
Sun, Yaoliang
;
Zheng, Zening
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/01/26