中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
昆明植物研究所 [1]
武汉物理与数学研究所 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2019 [8]
学科主题
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DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
期刊论文
OAI收割
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15
作者:
Zhang, Zongwang
;
Wu, Yanwei
;
Wu, Bing
;
Qi, Qing
;
Li, Heng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Systemic sclerosis
SAHH inhibitor
Fibrosis
Inflammation
Vasculopathy
TGF-beta
Reversible SAHH inhibitor ameliorates psoriasis-like skin inflammation in mice by modulating keratinocyte differentiation and reducing inflammatory infiltration via regulating DNA methylation of GATA3 and Lcn2
期刊论文
OAI收割
EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 卷号: 49, 页码: 1858-1858
作者:
Chen, L.
;
Lin, Z.
;
He, S.
;
Zuo, J.
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors
期刊论文
OAI收割
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:
Sajesh, Babu, V
;
On, Ngoc H.
;
Omar, Refaat
;
Alrushaid, Samaa
;
Kopec, Brian M.
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/12/20
blood-brain barrier (BBB)
drug delivery
transient modulation
HAV6 cadherin peptide
adenanthin
magnetic resonance imaging (MRI)
medulloblastoma
Recombinant Butelase-Mediated Cyclization of the p53-Binding Domain of the Oncoprotein MdmX-Stabilized Protein Conformation as a Promising Model for Structural Investigation
期刊论文
OAI收割
BIOCHEMISTRY, 2019, 卷号: 58, 期号: 27, 页码: 3005-3015
作者:
Pi, Ni
;
Gao, Meng
;
Cheng, Xiyao
;
Liu, Huili
;
Kuang, Zhengkun
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/10/14
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:
Li, Qiannan
;
Zhang, Tao
;
Li, Shiliang
;
Tong, Linjiang
;
Li, Junyu
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
EGFR
mutant
inhibitor
C797S
Assay development for determination of DZ2002, a new reversible SAHH inhibitor, and its acid metabolite DZA in blood and application to rat pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2019, 卷号: 9, 期号: 1, 页码: 25-33
作者:
Jia, Weiwei
;
Li, Jing
;
Du, Feifei
;
Sun, Yan
;
Xu, Fang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
S-adenosyl-L-homocysteine hydrolase
DZ2002
Carboxylesterases
Pharmacokinetics
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
OAI收割
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:
He, Shijun
;
Liu, Xing
;
Lin, Zemin
;
Liu, Yuting
;
Gu, Lei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage
期刊论文
OAI收割
Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1
作者:
He,Shijun
;
Liu,Xing
;
Lin,Zemin
;
Liu,Yuting
;
Gu,Lei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
SAHH inhibitor
Lupus nephritis
α-Actinin-4
Integrin-linked kinase
Integrin
Focal adhesion