机构

• 上海药物研究所 [8]
• 昆明植物研究所 [4]
• 上海生物化学与细胞生... [3]
• 计算技术研究所 [1]
• 上海营养与健康研究所 [1]
• 合肥物质科学研究院 [1]
• 更多

采集方式

• OAI收割 [20]

内容类型

• 期刊论文 [19]
• 学位论文 [1]

发表日期

• 2022 [2]
• 2021 [2]
• 2020 [2]
• 2019 [2]
• 2017 [3]
• 2016 [1]
• 更多

学科主题

• Biochemist... [1]
• Developmen... [1]
• Oncology [1]
• Research &... [1]
• Science & ... [1]

筛选

浏览/检索结果: 共20条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Solubilization, purification, and ligand binding characterization of G protein-coupled receptor SMO in native membrane bilayer using styrene maleic acid copolymer 期刊论文  OAI收割 PEERJ, 2022, 卷号: 10 作者:  Zhu, Lina;  Zhao, Hongxin;  Wang, Yizhuo;  Yu, Chuandi;  Liu, Juanjuan   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/12/23 GPCR  Dissociation constant  Detergents  Styrene maleic acid copolymer nanodiscs  Smoothened receptors  NMR   The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490 作者:  Zhang, Shaoqing;  Chen, Yue;  Xu, Zhongli;  Yang, Jun;  Sun, Renhong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/04/10 Hedgehog  Bcl-xL  PROTAC  drug resistance  bone growth   Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL MEDICINE, 2021, 卷号: 218, 期号: 9, 页码: 22 作者:  Guo, Duancheng;  Wang, Yuan;  Cheng, Yan;  Liao, Shengyou;  Hu, Jian   |  收藏  |  浏览/下载：25/0  |  提交时间：2021/12/01 Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504 作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian   |  收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 Medulloblastoma  Hedgehog signaling  pathway  Drug resistance  GLI  BRD4   Medulloblastoma: Molecular understanding, treatment evolution, and new developments 期刊论文  OAI收割 PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13 作者:  Liu, Xiaohua;  Ding, Chunyong;  Tan, Wenfu;  Zhang, Ao   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 Medulloblastoma  Pediatric brain tumor  Oncogenic driver gene  Hedgehog pathway inhibitor  Smoothened receptor antagonist   RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling 期刊论文  OAI收割 DEVELOPMENT, 2020 作者:  Ma, Pengcheng;  An, Tao;  Zhu, Liang;  Zhang, Longlong;  Wang, Huishan   |  收藏  |  浏览/下载：20/0  |  提交时间：2021/01/05 Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文  OAI收割 PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16 作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.   |  收藏  |  浏览/下载：79/0  |  提交时间：2019/12/20 blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma   Integrative analysis of gene expression and DNA methylation through one-class logistic regression machine learning identifies stemness features in medulloblastoma 期刊论文  OAI收割 MOLECULAR ONCOLOGY, 2019, 卷号: 13, 期号: 10, 页码: 2227-2245 作者:  Lian, Hao;  Han, Yi-Peng;  Zhao, Yang;  Li, Qi-Feng;  Wang, Bao-Cheng   |  收藏  |  浏览/下载：12/0  |  提交时间：2020/12/09 connectivity map  machine-learning methods  medulloblastoma  prognostic model  stemness  tumor immune environment   PEROXIREDOXIN1 IS A THERAPEUTIC TARGET IN GROUP-3 MEDULLOBLASTOMA 期刊论文  OAI收割 NEURO-ONCOLOGY, 2017, 卷号: 19, 页码: 200-200 作者:  Babu, Sajesh;  Omar, Refaat;  Fediuk, Holly;  Li, Lin;  Coudiere-Morrision, Ludivine   |  收藏  |  浏览/下载：19/0  |  提交时间：2018/05/08 Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 19, 页码: 8218-8245 作者:  Liu, Gang;  Huang, Wenjing;  Wang, Juan;  Liu, Xiaohua;  Yang, Jun   |  收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08