中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2021 [8]
学科主题
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发表日期:2021
专题:上海药物研究所
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Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
OAI收割
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
Structural insights into the activation of human calcium-sensing receptor
期刊论文
OAI收割
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 11
作者:
Xiong, Zhaoping
;
Cheng, Ziqiang
;
Lin, Xinyuan
;
Xu, Chi
;
Liu, Xiaohong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/11/04
federated learning
drug discovery
FedAMP
Non-IID data
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
期刊论文
OAI收割
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:
Liu, Ping
;
Cong, Xiaoji
;
Liao, Shengjie
;
Jia, Xinglong
;
Wang, Xiaomin
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/08/17
Identification of novel anti-inflammatory Nur77 modulators by virtual screening
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:
Ding, Xiaoyu
;
Zhao, Zijie
;
Wu, Yue
;
Zhang, Hao
;
Chen, Kaixian
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Nur77
Binding site evaluation
Virtual Screening
Inflammation
Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 6
作者:
Xiong, Fengmin
;
Ding, Xiaoyu
;
Zhang, Hao
;
Luo, Xiaomin
;
Chen, Kaixian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/08/17
Monoacylglycerol lipase
Inhibitor
Virtual screening
Inflammation
Molecular basis of ligand recognition and activation of human V2 vasopressin receptor
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 3
作者:
Zhou, Fulai
;
Ye, Chenyu
;
Ma, Xiaomin
;
Yin, Wanchao
;
Croll, Tristan I.
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Full-Length Transcriptome Analysis of Plasmodium falciparum by Single-Molecule Long-Read Sequencing
期刊论文
OAI收割
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2021, 卷号: 11, 页码: 11
作者:
Yang, Mengquan
;
Shang, Xiaomin
;
Zhou, Yiqing
;
Wang, Changhong
;
Wei, Guiying
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
Plasmodium falciparum
small protein
long non-coding RNA
alternative splicing
full-length RNA-seq