中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/09
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer
期刊论文
OAI收割
MATERIALS TODAY BIO, 2023, 卷号: 23, 页码: 16
作者:
Wang, Lu
;
Zhang, Tianyu
;
Zheng, Yile
;
Li, Yuting
;
Tang, Xiyuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Proteasome inhibitors reduce CD73 expression partly
via
decreasing p-ERK in NSCLC cells
期刊论文
OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:
Su, Ai-Ling
;
Tian, Chang-Qing
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
CD73
Proteasome inhibitors
ERK
NSCLC
Preparation of imidazole acids grafted chitosan with enhanced antioxidant, antibacterial and antitumor activities
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 315, 页码: 16
作者:
Ma, Bing
;
Zhang, Jingjing
;
Mi, Yingqi
;
Miao, Qin
;
Tan, Wenqiang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/15
Imidazole acids grafted chitosan
Antioxidant activity
Antibacterial activity
Antitumor activity
Redox-sensitive self-assembled micelles based on low molecular weight chitosan-lipoic acid conjugates for the delivery of doxorubicin: Effect of substitution degree of lipoic acid
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 247, 页码: 14
作者:
Yuan, Yuting
;
Wang, Zhenhua
;
Su, Shengjia
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Amphiphilic polymer
Doxorubicin
Drug delivery
Release-trigger release
Self-assembled micelle
Solasodine suppresses the metastasis of gastric cancer through claudin-2 via the AMPK/STAT3/NF-kappa B pathway
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 379, 页码: 12
作者:
Su, Kexin
;
Yao, Xuan
;
Guo, Chenxu
;
Qian, Chunmei
;
Wang, Yiying
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Solasodine
Gastric cancer
Claudin-2
AMPK
EMT
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:
Wang, Han-lin
;
Li, Jia-nan
;
Kan, Wei-juan
;
Xu, Gao-ya
;
Luo, Guang-hao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
acute myeloid leukemia
cytarabine
daunorubicin
idarubicin
drug resistant
multi-omics
autophagy
chloroquine phosphate