中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [122]
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Recent advances in antibody glycoengineering for the of functions
期刊论文
OAI收割
CURRENT OPINION IN CHEMICAL BIOLOGY, 2024, 卷号: 78, 页码: 10
作者:
Liu, Zhi
;
Zou, Xiangman
;
Tang, Feng
;
Huang, Wei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/06
Antibody glycoengineering
Endoglycosidase
Chemo-enzymatic
Glycosyltransferase
Antibody-drug conjugates
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
期刊论文
OAI收割
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 卷号: 17, 期号: 1, 页码: 32
作者:
Wei, Qing
;
Li, Peijing
;
Yang, Teng
;
Zhu, Jiayu
;
Sun, Lu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/27
Antibody-drug conjugate
Solid tumor
Combination therapy
Immunotherapy
Targeted therapy
Conference report for the 10th China Bioanalysis Forum annual meeting
期刊论文
OAI收割
BIOANALYSIS, 2023, 页码: 4
作者:
Dong, Kelly
;
Zhu, Mingshe
;
Tang, Daniel
;
Jin, Fan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/19
China Bioanalysis Forum
CBF
ICH M10
DMPK and Bioanalysis for New Modalities
C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13
作者:
Zeng, Yue
;
Shi, Wei
;
Liu, Zhi
;
Xu, Hao
;
Liu, Liya
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 7
作者:
Zhu, Xiao
;
Gong, Likun
;
Qin, Qiuping
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Antibody-dependent cell-mediated cytotoxicity
Time-resolved fluorescence
Monoclonal antibody
Antibody-Drug Conjugate
Eu
NK-92 cells
Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5
作者:
Wang, Yujie
;
Xu, Keshi
;
Liu, Hongchun
;
Zhang, Wei
;
Hu, Chun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/19
Auristatin E
beta-Glucuronidase
Antiproliferation
Tumor microenvironment
Redox-sensitive self-assembled micelles based on low molecular weight chitosan-lipoic acid conjugates for the delivery of doxorubicin: Effect of substitution degree of lipoic acid
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 247, 页码: 14
作者:
Yuan, Yuting
;
Wang, Zhenhua
;
Su, Shengjia
;
Mi, Yingqi
;
Li, Qing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Amphiphilic polymer
Doxorubicin
Drug delivery
Release-trigger release
Self-assembled micelle
Development of HSP90 inhibitors-SN38 conjugates for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11
作者:
Cao, Yuting
;
Shen, Qianqian
;
Ding, Mengyuan
;
Chen, Yi
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2023/10/17
HSP90
SN38 conjugate
Drug accumulation
Cancer treatment
Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Lu, Wei
;
Zhu, Shulei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2023/10/17
EGFR
HER2
NAMPT
Resistance
Selectivity
Molecular docking