中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [91]
上海生物化学与细胞... [83]
昆明植物研究所 [75]
过程工程研究所 [45]
武汉病毒研究所 [39]
西北高原生物研究所 [28]
更多
采集方式
OAI收割 [483]
iSwitch采集 [63]
内容类型
期刊论文 [512]
学位论文 [29]
会议论文 [4]
专著 [1]
发表日期
2021 [10]
2020 [18]
2019 [27]
2018 [30]
2017 [32]
2016 [28]
更多
学科主题
Pharmacol... [26]
Chemistry [20]
Gastroent... [19]
Virology [18]
Biochemis... [15]
Biochemis... [11]
更多
筛选
浏览/检索结果:
共546条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14
作者:
Yang, Li
;
Gong, Ying
;
Liu, Feifei
;
Chen, Wuhong
;
Wang, Xinran
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/19
Hepatitis B virus
Capsid assembly
Phthalazinone derivatives
Apoptosis
A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
期刊论文
OAI收割
NATURE METABOLISM, 2023, 页码: 35
作者:
Yang, Zijian
;
Yan, Cong
;
Ma, Jiaqiang
;
Peng, Panpan
;
Ren, Xuelian
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
A 33-residue peptide tag increases solubility and stability of Escherichia coli produced single-chain antibody fragments
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4614
作者:
Wang, Yang
;
Yuan, Wenjie
;
Guo, Siqi
;
Li, Qiqi
;
Chen, Xiaomei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 7, 页码: 14
作者:
Lin, Jian
;
Dai, Yuting
;
Sang, Chen
;
Song, Guohe
;
Xiang, Bin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/08/30
tumor microenvironment
cytotoxicity
immunologic
drug therapy
combination
Hemin protects against Zika virus infection by disrupting virus-endosome fusion
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2022, 卷号: 203, 页码: 11
作者:
Xu, Meng-Meng
;
Wu, Bing
;
Huang, Guan-Gen
;
Feng, Chun-Lan
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/08/16
Zika virus
Hemin
Antiviral
Inflammation
HO-1
Viral fusion
Cross Analysis of Genomic-Pathologic Features on Multiple Primary Hepatocellular Carcinoma
期刊论文
OAI收割
FRONTIERS IN GENETICS, 2022, 卷号: 13, 页码: 9
作者:
Ren, Fei
;
Wang, Depin
;
Zhang, Xueyuan
;
Zhao, Na
;
Wang, Xiaowen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/07/12
hepatocellular carcinoma
whole exome sequencing
whole slide images
molecular profiling and subtyping
hepatitis B virus
Aristolochic acids exposure was not the main cause of liver tumorigenesis in adulthood
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2252-2267
作者:
Chen, Shuzhen
;
Dong, Yaping
;
Qi, Xinming
;
Cao, Qiqi
;
Luo, Tao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/08/16
Aristolochic acids (AAs)
Mutational signature
AA-DNA adduct
Hepatocellular carcinoma (HCC)
Liver tumorigenesis
Hepatitis B virus (HBV)
Risk factors
Tumor prevention
Psoralen inhibits hepatitis B viral replication by down-regulating the host transcriptional machinery of viral promoters
期刊论文
OAI收割
VIROLOGICA SINICA, 2022, 卷号: 37, 期号: 2, 页码: 256-265
作者:
Ma, Xinna
;
Li, Heng
;
Gong, Ying
;
Liu, Feifei
;
Tong, Xiankun
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/08/16
Psoralen
Hepatitis B virus (HBV)
Forkhead box-O 1 (FOXO1)
Transcription
PPAR? co-activator 1? (PGC1?)