机构

• 上海药物研究所 [12]
• 昆明植物研究所 [2]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [15]

内容类型

• 期刊论文 [15]

发表日期

• 2021 [2]
• 2019 [2]
• 2018 [3]
• 2017 [2]
• 2016 [1]
• 2013 [1]
• 更多

学科主题

• Chemistry,... [1]
• Pharmacolo... [1]
• Plant Scie... [1]

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a novel 53BP1 inhibitor through AlphaScreen-based high-throughput screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 34, 页码: 116054 作者:  Sun, Yanli;  Lu, Haibo;  Fang, Xueyu;  Xiao, Senhao;  Yang, Feng   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/21 53BP1-TTD  H4K2Ome2  AlphaScreen  HTS  Novel inhibitor   Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start? 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15 作者:  Yu, Qing;  Sun, Yi   |  收藏  |  浏览/下载：26/0  |  提交时间：2021/03/15 anti-cancer drug  cullin-RING E3 ligases  natural product  high-throughput screen  neddylation  small-molecule inhibitors   Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 997-1007 作者:  Trevarton, Alexander J.;  Zhou, Yan;  Yang, Dehua;  Rewcastle, Gordon W.;  Flanagan, Jack U.   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Cancer  YB-1  Luciferase  AlphaScreen  Transcription factor  Single-stranded DNA   Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening 期刊论文  OAI收割 RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924 作者:  Tao, Hongru;  Wang, Jun;  Lu, Wenchao;  Zhang, Rukang;  Xie, Yiqian   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 9, 页码: 1544-1552 作者:  Lu, Tian;  Hu, Jun-chi;  Lu, Wen-chao;  Han, Jie;  Ding, Hong   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 AlphaScreen  high-throughput screening  SMARCA2  bromodomain  small molecule inhibitor   Design, synthesis and biological evaluation of benzo[cd]indo1-2(1H)-ones derivatives as BRD4 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 264-273 作者:  Feng, Yuxin;  Xiao, Senhao;  Chen, Yantao;  Jiang, Hao;  Liu, Na   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Benzo[cd]indol-2(1H)-one  Sulfonamide  BRD4 inhibitor  Bromodomain and extra-terminal domain  Acetyl-lysine binding pocket   A Highly Sensitive Non-Radioactive Activity Assay for AMP-Activated Protein Kinase (AMPK) 期刊论文  OAI收割 Methods and protocols, 2018, 卷号: 1, 期号: 1 作者:  Yan, Yan;  Gu, Xin;  Xu, H Eric;  Melcher, Karsten   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 Discovery of novel trimethoxy-ring BRD4 bromodomain inhibitors: AlphaScreen assay, crystallography and cell-based assay 期刊论文  OAI收割 MEDCHEMCOMM, 2017, 卷号: 8, 期号: 6, 页码: 1322-1331 作者:  Chen, Zhifeng;  Zhang, Hao;  Liu, Shien;  Xie, Yiqian;  Jiang, Hao   |  收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08 Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 9, 页码: 2003-2009 作者:  Sun, Zhongya;  Zhang, Hao;  Chen, Zhifeng;  Xie, Yiqian;  Jiang, Hao   |  收藏  |  浏览/下载：89/0  |  提交时间：2019/01/08 BRD4 inhibitor  High-throughput screening  Crystallography   Generation and characterization of a human nanobody against VEGFR-2 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 6, 页码: 857-864 作者:  Ma, Lin;  Gu, Kai;  Zhang, Cheng-hai;  Chen, Xue-tao;  Jiang, Yi   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 nanobody  VEGFR2  anticancer agent  anti-angiogenesis  phage display