中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [72]
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期刊论文 [184]
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Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
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收藏
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浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Advancements and Obstacles of PARP Inhibitors in Gastric Cancer
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 19
作者:
Chen, Hongjie
;
Hu, Yangchan
;
Zhuang, Zirui
;
Wang, Dingyi
;
Ye, Zu
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收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/12/19
gastric cancer
DNA damage repair
PARP inhibitor
cancer therapy
We extend our gratitude to all researchers for their insightful investigations into PARP and PARPi within the context of gastric cancer.
项目
OAI收割
资助机构: We extend our gratitude to all researchers for their insightful investigations into PARP and PARPi within the context of gastric cancer., 2023-
-
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收藏
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浏览/下载:3/0
  |  
提交时间:2023/12/19
YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 20
作者:
Sun, Yuting
;
Yang, Hui
;
Yuan, Jiaqi
;
Wang, Limin
;
Song, Shanshan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
基于有害结局路径网络的有机磷酸酯毒性筛查及机制研究
学位论文
OAI收割
: 中国科学院烟台海岸带研究所, 2023
作者:
王晓晴
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收藏
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浏览/下载:11/0
  |  
提交时间:2023/06/28
新污染物
有机磷酸酯
有害结局路径网络
计算毒理学
风险预测与评估
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 108
作者:
Hu, Yiqun
;
Wen, Qingliang
;
Cai, Yefeng
;
Liu, Yunye
;
Ma, Wenli
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收藏
  |  
浏览/下载:36/0
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提交时间:2022/12/23
Alantolactone
Anaplastic thyroid cancer
ROS
Pyroptosis
Apoptosis
Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 卷号: 13, 期号: 1, 页码: 161-+
作者:
Li, Yongpeng
;
Li, Lin
;
Fu, Haoyu
;
Yao, Qing
;
Wang, Lei
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收藏
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浏览/下载:11/0
  |  
提交时间:2023/10/17
Antibody-drug conjugate
DS-8201
PARP
ATR
synergy
DNA damage
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
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收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors (vol 0, pg 1, 2022)
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-zhen
;
Ma, Li-ying
;
Zhang, Zong-hui
;
Wang, Xiao-lin
;
Hua, Jing-han
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收藏
  |  
浏览/下载:27/0
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提交时间:2022/12/23