机构

• 上海药物研究所 [23]
• 大连化学物理研究所 [6]
• 上海有机化学研究所 [5]
• 化学研究所 [4]
• 兰州化学物理研究所 [4]
• 金属研究所 [3]
• 更多

采集方式

• OAI收割 [60]
• iSwitch采集 [3]

内容类型

• 期刊论文 [63]

发表日期

• 2023 [1]
• 2022 [1]
• 2021 [2]
• 2019 [6]
• 2018 [3]
• 2017 [1]
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学科主题

• Pharmacolo... [3]
• 有机氟化学 [3]
• 物理化学与绿色催化 [3]
• Chemistry [2]
• Analysis [1]
• Chemistry,... [1]
• 更多

筛选

浏览/检索结果: 共63条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Synthesis and biological evaluation of pyrazole-fused oleanolic acid derivatives as novel inhibitors of inflammatory and osteoclast differentiation 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 80, 页码: 117177 作者:  Yu, Yuanyuan;  Yuan, Wenlong;  Yuan, Jiaqi;  Wei, Wenhui;  He, Qian   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Osteoarthritis  Oleanolic acid derivatives  Anti-inflammatory  IL-1? inhibition  Antiosteoclastic activity   Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15 作者:  Zhu, Cheng-Liang;  Luo, Xiaomin;  Tian, Tian;  Rao, Zijian;  Wang, Hanlin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16 AKT  Protein kinase B  PROTAC  Chemical degrader  Rational design   Synthesis and Biological Evaluation of C-17-Amino-Substituted Pyrazole-Fused Betulinic Acid Derivatives as Novel Agents for Osteoarthritis Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 18, 页码: 13676-13692 作者:  Wang, Jie;  Wei, Wenhui;  Zhang, Xiaofei;  Cao, Shiqi;  Hu, Bintao   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12 作者:  Lin, Tingting;  Li, Jiacheng;  Liu, Liping;  Li, Yuanqing;  Jiang, Hualiang   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24 CDK2 inhibitor  Selectivity  Anti-proliferative potency   fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85 作者:  Zhan, Wenhu;  Che, Jinxin;  Xu, Lei;  Wu, Yizhe;  Hu, Xiaobei   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Pyrazole-thiophene derivatives  Akt inhibitor  Antitumor   Pd-Catalyzed intramolecular C-H activation and C-S formation to synthesize pyrazolo[5,1-b]benzothiazoles without an additional oxidant 期刊论文  OAI收割 ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3234-3237 作者:  Peng, Yingyuan;  He, Qian;  Zhang, Xiaofei;  Yang, Chunhao   |  收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 Discovery of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 10, 页码: 1187-1193 作者:  Sun, Liangpeng;  Wang, Peipei;  Xu, Lili;  Gao, Lixin;  Li, Jia   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 PTP1B inhibitor  1,3-Diphenyl-1H-pyrazole  Rhodanine-3-alkanoic acid   An organocatalytic asymmetric Mannich reaction of pyrazoleamides with cyclic trifluoromethyl ketimines: enantioselective access to dihydroquinazolinone skeletons 期刊论文  OAI收割 ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 16, 期号: 18, 页码: 3372-3375 作者:  Luo, Yuan;  Xie, Ke-Xin;  Yue, Deng-Feng;  Zhang, Xiao-Mei;  Xu, Xiao-Ying   |  收藏  |  浏览/下载：32/0  |  提交时间：2020/12/24 Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294 作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun   |  收藏  |  浏览/下载：113/0  |  提交时间：2019/03/18 Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)   A dual approach to study the synthesis, crystal structure and nonlinear optical properties of binuclear Pd(II) complex of 3-methyl-5-(trifluoromethyl) pyrazole and its potential quantum chemical analogues 期刊论文  OAI收割 INORGANICA CHIMICA ACTA, 2019, 卷号: 494, 页码: 160-167 作者:  Muhammad, S;  Hussain, S;  Chen, XN;  Al-Sehemi, AG;  Li, ZJ   |  收藏  |  浏览/下载：98/0  |  提交时间：2020/10/16 PALLADIUM COMPLEXES  MOLECULAR CALCULATIONS  ABSOLUTE HARDNESS  TRANSITION  HYPERPOLARIZABILITIES  DERIVATIVES  DINUCLEAR  EFFICIENT  COPPER(I)  ENERGIES