中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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机构
上海药物研究所 [4]
上海生物化学与细胞生... [3]
上海营养与健康研究所 [3]
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OAI收割 [14]
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期刊论文 [14]
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2023 [2]
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Cell Biolo... [2]
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Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted delivery
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2023, 卷号: 42, 期号: 1, 页码: 20
作者:
Long, Li
;
Xiong, Wei
;
Lin, Fenwang
;
Hou, Jiazhen
;
Chen, Guihua
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Shikonin
Colorectal cancer liver metastasis
Glycolysis
Pyruvate kinase M2 (PKM2)
Epithelial-mesenchymal transition (EMT)
Immune microenvironment
Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2608-2621
作者:
Wang, Jingyao
;
Zhou, Shaoqing
;
Cheng, Yan
;
Cheng, Lin
;
Qin, Ying
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27
Rhubarb granule promotes diethylnitrosamine-induced liver tumorigenesis by activating the oxidative branch of pentose phosphate pathway via G6PD in rats
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 281
作者:
Huang, Hongwu
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/11/15
Rhubarb
Hepatocarcinogenesis
Diethylnitrosamine
The pentose phosphate pathway
Glucose 6 phosphate dehydrogenase
Iridin Prevented Against Lipopolysaccharide-Induced Inflammatory Responses of Macrophages via Inactivation of PKM2-Mediated Glycolytic Pathways
期刊论文
OAI收割
JOURNAL OF INFLAMMATION RESEARCH, 2021, 卷号: 14
作者:
Ying, Zhen-Hua
;
Li, Hui-Min
;
Yu, Wen-Ying
;
Yu, Chen-Huan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/04/26
isoflavone
glycolysis
Warburg effect
PKM2
JAK/STATs
NF-kappa B
Glycolysis is suppressed by DCZ0801-induced inactivation of the Akt/mTOR pathway in Multiple Myeloma
期刊论文
OAI收割
JOURNAL OF CANCER, 2020, 卷号: 11, 期号: 16, 页码: 4907-4916
作者:
Feng, Qilin
;
Yao, Qingchun
;
Li, Bo
;
Xie, Yongsheng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
DCZ0801
multiple myeloma
apoptosis
cell cycle
glycolysis
DNA methylation modifier LSH inhibits p53 ubiquitination and transactivates p53 to promote lipid metabolism
期刊论文
OAI收割
EPIGENETICS & CHROMATIN, 2019, 卷号: 12, 期号: 1, 页码: 22
作者:
Chen, Ling
;
Shi, Ying
;
Liu, Na
;
Wang, Zuli
;
Yang, Rui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
LSH
P53
DUB
PKM2
Lipid metabolism
High PKM2 expression is independently correlated with decreased overall survival in hepatocellular carcinoma
期刊论文
OAI收割
ONCOLOGY LETTERS, 2018, 期号: 16, 页码: 3603-3610
作者:
DONG‑HUI LU
;
YUE-DONG GAO
;
WEN‑XING LI
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2018/09/26
Pyruvate Kinase Muscle Isozyme M2
Hepatocellular Carcinoma
Clinical Features, Overall Survival
Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 17, 页码: 6623-6634
作者:
Zhao, Xiaoping
;
Zhao, Li
;
Li, Jiajin
;
Min, Xuejie
;
Liu, Jianjun
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/09
lipid metabolism
gene transcription
hepatocellular carcinoma
lipid synthesis
lipogenesis
cell proliferation
liver cancer
pyruvate kinase
PKM2
SREBP-1a
sterol regulatory element-binding protein
Structural basis of PKM2 regulation
期刊论文
OAI收割
PROTEIN & CELL, 2015, 卷号: 6, 期号: 4, 页码: 238-240
作者:
Yang, WW
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/07/22
Pyruvate kinase M2 at a glance
期刊论文
OAI收割
JOURNAL OF CELL SCIENCE, 2015, 卷号: 128, 期号: 9, 页码: 1655-1660
作者:
Yang, WW
;
Lu, ZM
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/07/22
PKM2
Pyruvate kinase M2
Metabolism reprogramming
Protein kinase
Gene transcription