机构

• 上海药物研究所 [4]
• 上海生物化学与细胞生... [2]
• 水生生物研究所 [1]
• 中国科学院大学 [1]

采集方式

• OAI收割 [7]
• iSwitch采集 [1]

内容类型

• 期刊论文 [8]

发表日期

• 2020 [2]
• 2018 [1]
• 2016 [1]
• 2015 [2]
• 2011 [1]
• 2009 [1]
• 更多

学科主题

• Cell Biolo... [1]
• Genetics &... [1]

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10 作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 Histone methylation  SET7  Small-molecule inhibitor  Virtual screening  Molecular probe   Computational discovery and biological evaluation of novel inhibitors targeting histone-lysine N-methyltransferase SET7 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 7, 页码: 10 作者:  Min, Wenjian;  Hou, Zeng;  Zhang, Fang;  Xie, Shengnan;  Yuan, Kai   |  收藏  |  浏览/下载：13/0  |  提交时间：2020/07/01 Histone methylation  Lysine methyltransferase  SET7  Small-molecule inhibitor  Virtual screening   Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search 期刊论文  OAI收割 MOLECULES, 2018, 卷号: 23, 期号: 3 作者:  Ding, Hong;  Lu, Wen Chao;  Hu, Jun Chi;  Liu, Yu-Chih;  Zhang, Chen Hua   |  收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 SET7  inhibitor  similarity search  ligand-based drug design  chemical biology probe   Set7 mediated gli3 methylation plays a positive role in the activation of sonic hedgehog pathway in mammals 期刊论文  iSwitch采集 Elife, 2016, 卷号: 5, 页码: 19 作者:  Fu, Lin;  Wu, Hailong;  Cheng, Steven Y.;  Gao, Daming;  Zhang, Lei 收藏  |  浏览/下载：22/0  |  提交时间：2019/05/09 Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 20, 页码: 8166-8181 作者:  Meng, Fanwang;  Cheng, Sufang;  Ding, Hong;  Liu, Shien;  Liu, Yan   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Repression of hypoxia-inducible factor alpha signaling by Set7-mediated methylation 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2015, 卷号: 43, 期号: 10, 页码: 5081-5098 作者:  Liu, Xing;  Chen, Zhu;  Xu, Chenxi;  Leng, Xiaoqian;  Cao, Hong 收藏  |  浏览/下载：39/0  |  提交时间：2015/09/15 Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins 期刊论文  OAI收割 JOURNAL OF MOLECULAR CELL BIOLOGY, 2011, 卷号: 3, 期号: 5, 页码: 293-300 作者:  Xu, ST;  Zhong, C;  Zhang, TL;  Ding, JP 收藏  |  浏览/下载：11/0  |  提交时间：2015/07/22 Smyd2  Smyd proteins  SET family  histone lysine methyltransferase  epigenetics   The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation 期刊论文  OAI收割 NATURE GENETICS, 2009, 卷号: 41, 期号: 1, 页码: 125-129 作者:  Wang, J;  Hevi, S;  Kurash, JK;  Lei, H;  Gay, F 收藏  |  浏览/下载：60/0  |  提交时间：2015/07/22