中国科学院机构知识库网格
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Ascorbic Acid Reprograms Epigenome and Epitranscriptome by Reducing Fe(III) in the Catalytic Cycle of Dioxygenases
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 1, 页码: 129-140
作者:
He, Weizhi
;
Yin, Xiaotong
;
Xu, Chu
;
Liu, Xiangyue
;
Huang, Yue
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/27
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming
期刊论文
OAI收割
DIABETES, 2023, 卷号: 72, 期号: 11, 页码: 24
作者:
Pan, Xiaowen
;
Ye, Lingxia
;
Guo, Xiaozhen
;
Wang, Weihua
;
Zhang, Ziyin
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Chemical Inhibitors Targeting the Oncogenic m
6
A Modifying Proteins
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022
作者:
Huang, Yue
;
Xia, Wenyang
;
Dong, Ze
;
Yang, Cai-Guang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/11
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Tang, Hairong
;
Yu, Aisong
;
Xing, Li
;
Chen, Xiaoyu
;
Ding, Huaqian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
The Changes of Histone Methylation Induced by Adolescent Social Stress Regulate the Resting-State Activity in mPFC
期刊论文
OAI收割
Research, 2023, 期号: 6, 页码: 12
作者:
Jiesi Wang
;
Wei Zhang
;
Hang Xu
;
Bart Ellenbroek
;
Jiajie Dai
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/11/27
Current insights into posttranscriptional regulation of fleshy fruit ripening
期刊论文
OAI收割
PLANT PHYSIOLOGY, 2023, 卷号: 192, 期号: 3, 页码: 1785-1798
作者:
Wang, Weihao
;
Wang, Yuying
;
Chen, Tong
;
Qin, Guozheng
;
Tian, Shiping
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/07
Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation
期刊论文
OAI收割
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9, 页码: 23
作者:
Yang, Zhen
;
Xu, Feng
;
Teschendorff, Andrew E.
;
Zhao, Yi
;
Yao, Lei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/07/12
lncRNA
circRNA
DNA methylation
histone modification
transcriptional regulation
regulatory network
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis
期刊论文
OAI收割
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:
Wang, Jin
;
Xie, Si-an
;
Li, Ning
;
Zhang, Tao
;
Yao, Weijuan
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/10
Matrix stiffness
Inflammation
DDR1
DNMT1
Mechanotransduction