中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
大连化学物理研究所 [2]
昆明植物研究所 [1]
中国科学院大学 [1]
兰州化学物理研究所 [1]
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OAI收割 [18]
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期刊论文 [17]
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浏览/检索结果:
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Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:
Gu, Zhanni
;
Wu, Lingyan
;
Duan, Yanan
;
Wang, Jiang
;
Zhou, Shengbin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Adenosine 5 '-monophosphate-activated protein kinase
AMPK activators
Berberine
Tetrahydroberberine
T2DM
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:
Zhou, Shengbin
;
Duan, Yanan
;
Wang, Jiang
;
Zhang, Jin
;
Sun, Haifeng
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Tetrahydroberberine
4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines
Mitochondrial respiration
AMPK indirect activators
db/db mice
Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta
期刊论文
OAI收割
NEUROPHARMACOLOGY, 2010, 卷号: 59, 期号: 7-8, 页码: 567-572
作者:
Wu, Chen
;
Yang, Kechun
;
Liu, Qiang
;
Wakui, Matoko
;
Jin, Guo-Zhang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Tetrahydroberberine
Dopaminergic neurons
Substantia nigra compacta
ATP-sensitive K+ channel
Rotenone
Parch-clamp
Determination of alkaloids in corydalis yanhusuo using hollow-fibre liquid phase microextraction and high performance liquid chromatography
期刊论文
iSwitch采集
Chemical papers, 2009, 卷号: 63, 期号: 3, 页码: 351-357
作者:
Lu, Huawei
;
Sun, Huanquan
;
Liu, Xia
;
Jiang, Shengxiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/05/10
Corydalis yanhusuo
Alkaloid
Hollow fibre
Liquid phase microextraction
Hplc
NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine
期刊论文
OAI收割
Chinese Journal of Magnetic Resonance, 2009, 卷号: 26, 期号: 1, 页码: 111-119
作者:
ZHANG Pei-xuan
;
LI Jian-feng
;
WEI Ya-bing
;
SHEN Jing-shan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
nuclear magnetic resonance
structure elucidation
mass spectrometry
fluoro tetrahydroberberine
Chiral high-performance liquid chromatographic separation of the enantiomers of tetrahydropalmatine and tetrahydroberberine, isolated from Corydalis yanhusuo
期刊论文
OAI收割
Anal Bioanal Chem, 2006, 卷号: 384, 页码: 939-945
作者:
Shi YP(师彦平)
;
Shi YP(师彦平)
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2012/10/14
Enantiomer separation
Polysaccharide carbamate phase
Specific rotation
Circular dichroism
Tetrahydropalmatine
Tetrahydroberberine
Investigation of the metabolism of 7-(4-chlorbenzyl)7,8,13,13a-tetrahydroberberine chloride in the rat
期刊论文
OAI收割
european journal of drug metabolism and pharmacokinetics, 1998, 卷号: 23, 期号: 1, 页码: 41-44
作者:
Feng, N
;
Zhang, Z
;
An, D
;
Huang, W
;
Wang, G
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2015/11/09
metabolism
7-(4-chlorbenzyl)-7
rat
LC/MS
LC/NMR
8
13
13a-tetrahydroberberine chloride
Tetrahydroberberine blocks membrane K+ channels underlying its inhibition of intracellular message-mediated outward currents in acutely dissociated CA1 neurons from rat hippocampus
期刊论文
OAI收割
BRAIN RESEARCH, 1997, 卷号: 775, 期号: 1-2, 页码: 214-218
作者:
Wu, J
;
Jin, GZ
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
tetrahydroberberine
K+ current
K+ channel
hippocampus
dissociated neuron
patch clamp
Identification of the metabolite of 7-(4-Chlorbenzyl)-7,8,13,13a-tetrahydroberberine chloride in rat bile by LC/MS and LC/NMR
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 1997, 卷号: 8, 期号: 6, 页码: 515-518
作者:
Feng, NP
;
Zhang, ZX
;
An, DK
;
Huang, WL
;
Wang, GJ
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/06/20