机构

• 上海药物研究所 [43]
• 过程工程研究所 [8]
• 合肥物质科学研究院 [4]
• 宁波材料技术与工程研... [3]
• 化学研究所 [3]
• 大连化学物理研究所 [3]
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• OAI收割 [88]
• iSwitch采集 [3]

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• 期刊论文 [88]
• 学位论文 [3]

发表日期

• 2023 [3]
• 2022 [7]
• 2021 [5]
• 2020 [6]
• 2019 [7]
• 2018 [11]
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学科主题

• Chemistry [2]
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• Virology [1]

筛选

浏览/检索结果: 共91条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14 作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Otilonium Bromide  Deubiquitinase  USP28  Selective inhibitor   YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 20 作者:  Sun, Yuting;  Yang, Hui;  Yuan, Jiaqi;  Wang, Limin;  Song, Shanshan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Discovery of Novel Drug-like PHGDH Inhibitors to Disrupt Serine Biosynthesis for Cancer Therapy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 21 作者:  Gao, Dingding;  Tang, Shuai;  Cen, Yixin;  Yuan, Liang;  Lan, Xiaojing   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555 作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 DNMT1 inhibitor  A549 cell lines  HCT116 cell lines  antitumor activity  pharmacokinetic   Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer 期刊论文  OAI收割 CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 8, 页码: 15 作者:  Wang, Ya-fang;  Yu, Lei;  Hu, Zong-long;  Fang, Yan-fen;  Shen, Yan-yan   |  收藏  |  浏览/下载：18/0  |  提交时间：2022/11/11 NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 6, 页码: 2859-2868 作者:  Wu, Ying;  Pu, Congying;  Fu, Yixian;  Dong, Guoqiang;  Huang, Min   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/21 NAMPT  Non-enzymatic function  eNAMPT  Cancer  MDSC  PROTAC  Tumor immunity  Immunotherapy   High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14 作者:  Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/06/15 Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文  OAI收割 LEUKEMIA, 2022 作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng   |  收藏  |  浏览/下载：68/0  |  提交时间：2022/02/14 Engineering Single-Atom Iron Nanozymes with Radiation-Enhanced Self-Cascade Catalysis and Self-Supplied H2O2 for Radio- enzymatic Therapy 期刊论文  OAI收割 ACS NANO, 2022, 卷号: 16, 期号: 11, 页码: 18849-18862 作者:  Zhu, XY;  Wu, JB;  Liu, RX;  Xiang, HD;  Zhang, WQ   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/11/09 single-atom iron nanozyme  external-?eld-enhanced catalysis  enzymatic therapy  radiotherapy   Ultrasound-directed enzyme-prodrug therapy (UDEPT) self-immolative doxorubicin derivatives 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 10, 页码: 4791-4801 作者:  Roemhild, Karolin;  Besse, Helena C.;  Wang, Bi;  Pena, Quim;  Sun, Qingxue   |  收藏  |  浏览/下载：12/0  |  提交时间：2022/08/16 Cancer  Prodrugs  Focused ultrasound  HIFU  beta-glucuronidase