中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
采集方式
OAI收割 [4]
内容类型
期刊论文 [4]
发表日期
2024 [1]
2022 [2]
2019 [1]
学科主题
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Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
Current Analytical Strategies for Antibody-Drug Conjugates in Biomatrices
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 19, 页码: 17
作者:
Qin, Qiuping
;
Gong, Likun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/11/11
ADC
antibody
payload
LBA
LC-MS
bioanalysis
immunogenicity
interference
Development and validation of a ligand-binding assay for quantification of the F(ab')(2) antivenom of Daboia russelii siamensis in human serum and its application to a phase I clinical study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 212, 页码: 8
作者:
Gui, Yuzhou
;
Yu, Chengyin
;
Zhou, Jiaye
;
Xin, Liang
;
Chen, Ze
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/06/15
F(ab')(2) antivenom
Daboia russelii siamensis
Ligand-binding assay
Method validation
Clinical trial
Two validated liquid chromatography-mass spectrometry methods with different pretreatments for the quantification of an anti-CD47 monoclonal antibody in rat and cynomolgus monkey serum compared with an electrochemiluminescence method
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 175, 页码: 11
作者:
Gao, Yuxiong
;
Zhang, Dan
;
Yang, Changyong
;
Duan, Xiaotao
;
Li, Xiuli
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Anti-CD47 monoclonal antibody
LC-MS
Adsorption issue
Electrochemiluminescence
Pharmacokinetics
Cross-validation