中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
作者:
Pauline Macheboeuf
;
Delphine S Fischer
;
Tom Brown Jr
;
Astrid Zervosen
;
Andre´Luxen
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2017/07/21
High spatial variability in water use efficiency of terrestrial ecosystems throughout China is predominated by biological factors
期刊论文
OAI收割
AGRICULTURAL AND FOREST METEOROLOGY, 2024, 卷号: 345, 页码: 109834
作者:
Dou, Xiaojun
;
Yu, Guirui
;
Chen, Zhi
;
Yang, Meng
;
Hao, Tianxiang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/02/05
Water use efficiency
Spatial variability
Influencing factors
Driving mechanism
Eddy covariance
Terrestrial ecosystems
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G
s
proteins
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 13
作者:
Cong, Zhaotong
;
Zhao, Fenghui
;
Li, Yang
;
Luo, Gan
;
Mai, Yiting
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/13
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:
Feng, Dazhi
;
Liu, Bo
;
Chen, Zhiwei
;
Xu, Jinyi
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/02/27
HPK1 inhibitor
machine learning
virtual screening
free energy perturbation
structural modification
Drivers of contemporary and future changes in Arctic seasonal transition dates for a tundra site in coastal Greenland
期刊论文
OAI收割
GLOBAL CHANGE BIOLOGY, 2024, 卷号: 30, 期号: 1, 页码: 17
作者:
Liu, Yijing
;
Wang, Peiyan
;
Elberling, Bo
;
Westergaard-Nielsen, Andreas
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/22
Arctic tundra ecosystem
climate change
projection
seasonal transition dates
snow cover
Structural framework for the understanding spectroscopic and functional signatures of the cyanobacterial Orange Carotenoid Protein families
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 254, 页码: 20
作者:
Sluchanko, Nikolai N.
;
Maksimov, Eugene G.
;
Slonimskiy, Yury B.
;
Varfolomeeva, Larisa A.
;
Bukhanko, Antonina Y.
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Photoprotection
Phycobilisome fluorescence quenching
Crystal structure
Protein-protein interaction
Absorption spectroscopy
Photoactivity
SEC-MALS
Heat sensitive E-helix cut ferritin nanocages for facile and high-efficiency loading of doxorubicin
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 253
作者:
Xia, Haining
;
Xu, Huangtao
;
Wang, Jiarong
;
Wang, Changhao
;
Chen, Ruiguo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/11/17
Ferritin nanocages
Drug loading
Structural modification
Thermal response
Ion-assisted
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants