机构

• 上海药物研究所 [9]

采集方式

• OAI收割 [9]

内容类型

• 期刊论文 [9]

发表日期

• 2020 [9]

学科主题

筛选

浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2020     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802 作者:  Lv, Kaikai;  Chen, Weicong;  Chen, Danqi;  Mou, Jie;  Zhang, Huijie   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/12/21 Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction 期刊论文  OAI收割 INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713 作者:  Damaneh, Mohammadali Soleimani;  Hu, Jian-Ping;  Huan, Xia-Juan;  Song, Shan-Shan;  Tian, Chang-Qing   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/07/01 BET inhibitor  Cell proliferation  Apoptosis  Anti-cancer agent   BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis 期刊论文  OAI收割 THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12 作者:  Li, Guang;  Zheng, Yan-Hua;  Xu, Li;  Feng, Juan;  Tang, Hai-Long   |  收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24 apoptosis  BRD4 inhibitor  G1 phase cell cycle checkpoint  multiple myeloma   Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 3956-3975 作者:  Li, Zizhou;  Xiao, Senhao;  Yang, Yaxi;  Chen, Chao;  Lu, Tian   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 BRD4 as a therapeutic target for nonfunctioning and growth hormone pituitary adenoma 期刊论文  OAI收割 NEURO-ONCOLOGY, 2020, 卷号: 22, 期号: 8, 页码: 1114-1125 作者:  Shi, Chengzhang;  Ye, Zhao;  Han, Jie;  Ye, Xiaoqing;  Lu, Wenchao   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/21 Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292 作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 CBP bromodomain  small-molecule inhibitor  high-throughput screening  TR-FRET  molecular modeling  human leukemia MV4-11 cells   A patent review of BRD4 inhibitors (2013-2019) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2020, 卷号: 30, 期号: 1, 页码: 57-81 作者:  Lu, Tian;  Lu, Wenchao;  Luo, Cheng   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 Bromodomain-containing protein 4 (BRD4)  bromodomain and extra-terminal (BET) family  small molecule inhibitors  cancer  patent  therapeutic potential