机构

• 上海药物研究所 [5]
• 过程工程研究所 [1]
• 自动化研究所 [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [6]
• 学位论文 [1]

发表日期

• 2020 [7]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2020     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11 作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling   |  收藏  |  浏览/下载：52/0  |  提交时间：2020/12/24 IDH1  gliomas  molecular docking  virtual screening  docking-based virtual screening   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Metabolic engineering of Cupriavidus necator H16 for improved chemoautotrophic growth and PHB production under oxygen-limiting conditions 期刊论文  OAI收割 METABOLIC ENGINEERING, 2020, 卷号: 61, 页码: 11-23 作者:  Tang, Ruohao;  Weng, Caihong;  Peng, Xiaowei;  Han, Yejun   |  收藏  |  浏览/下载：18/0  |  提交时间：2021/03/29 Cupriavidus necator H16  Carbon dioxide  Oxygen-limiting conditions  Transcription  Metabolic engineering  Ployhydroxybutyrate   Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi   |  收藏  |  浏览/下载：54/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   Mutant isocitrate dehydrogenase driven metabolic reprogramming results in therapeutic vulnerability to lactate dehydrogenase inhibition 期刊论文  OAI收割 CANCER RESEARCH, 2020, 卷号: 80, 期号: 16, 页码: 2 作者:  Bi, Aiwei;  Xu, Jun;  Jin, Nan;  Lan, Xiaojing;  Tang, Shuai   |  收藏  |  浏览/下载：18/0  |  提交时间：2021/05/24 基于定量磁共振影像组学的脑肿瘤无创诊断研究 学位论文  OAI收割 中国科学院自动化研究所: 中国科学院大学, 2020 作者:  张帅通   |  收藏  |  浏览/下载：55/0  |  提交时间：2020/06/12 磁共振影像（MRI）  影像组学  无创诊断  半监督学习  脑肿瘤