机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2024 [1]
• 2022 [3]
• 2021 [3]
• 2019 [1]
• 2018 [3]
• 2013 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 12 作者:  Zhang, Shunan;  Lai, Yi;  Pan, Jiaxing;  Saeed, Madiha;  Li, Shiqin   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/04/09 active tumor targeting  nanosensitizer  PROTAC prodrug  radiation therapy  tumor microenvironment   Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 22 作者:  Wang, Ao;  Luo, Xianggang;  Wang, Yawan;  Meng, Xin;  Lu, Zhengyu   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/11/11 Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 2, 页码: 1243-1264 作者:  Liang, Xuewu;  Tang, Shuai;  Liu, Xuyi;  Liu, Yingluo;  Xu, Qifu   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/06/15 The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490 作者:  Zhang, Shaoqing;  Chen, Yue;  Xu, Zhongli;  Yang, Jun;  Sun, Renhong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/04/10 Hedgehog  Bcl-xL  PROTAC  drug resistance  bone growth   MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice 期刊论文  OAI收割 METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 119, 页码: 12 作者:  Xu, Xiaoding;  Dong, Yunxia;  Ma, Ningning;  Kong, Weiwen;  Yu, Chuwei   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/08/17 miR-337-3p  PCSK9  LDL-C  Hyperlipidemia  Dual regulation   A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway 期刊论文  OAI收割 Cancer Cell International, 2021, 卷号: 21, 期号: 1 作者:  Gao,Xuejie   |  收藏  |  浏览/下载：41/0  |  提交时间：2021/06/11 Multiple myeloma  Anti-tumor activity  NF-κB   A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-kappa B pathway 期刊论文  OAI收割 CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 10 作者:  Gao, Xuejie;  Li, Bo;  Ye, Anqi;  Wang, Houcai;  Xie, Yongsheng   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17 Multiple myeloma  Anti-tumor activity  NF-kappa B   DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2 期刊论文  OAI收割 CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808 作者:  Kong, Yuanyuan;  Li, Bo;  Chang, Shuaikang;  Gao, Lu;  Xu, Zhijian   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 DCZ0814  multiple myeloma  mTOR  bone marrow microenvironment  apoptosis   Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 2, 页码: 823-834 作者:  Xie, Yongsheng;  Li, Bo;  Bu, Wenxuan;  Gao, Lu;  Zhang, Yong   |  收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 mantle cell lymphoma  dihydrocelastrol  apoptosis  cell cycle  mTORC1  mTORC2   Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy 期刊论文  OAI收割 NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91 作者:  Guo, Xiaodan;  Lv, Jianlu;  Lu, Jian;  Fan, Lei;  Huang, Xi   |  收藏  |  浏览/下载：53/0  |  提交时间：2019/01/08 Alzheimer's disease  Ginseng  Autophagy  BACE1  ER stress  Amyloid beta  Apoptosis  APP/PS1 transgenic mice