中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
上海营养与健康研究... [14]
生态环境研究中心 [6]
地球化学研究所 [4]
植物研究所 [3]
数学与系统科学研究院 [2]
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OAI收割 [60]
内容类型
期刊论文 [60]
发表日期
2019 [60]
学科主题
Oncology [4]
Biochemist... [3]
Plant Scie... [3]
Science & ... [3]
Cell Biolo... [2]
Chemistry [2]
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浏览/检索结果:
共60条,第1-10条
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发表日期:2019
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Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Targeting epigenetic machinery: Emerging novel allosteric inhibitors
期刊论文
OAI收割
PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24
作者:
Ye, Fei
;
Huang, Jing
;
Wang, Hongbo
;
Luo, Cheng
;
Zhao, Kehao
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Epigenetics
PRC2
MLL complex
SWI/SNF
DNMT1
allosteric inhibitors
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:
Zhang, Kai-li
;
Shen, Qian-qian
;
Fang, Yan-fen
;
Sun, Yi-ming
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
PRC2
EZH2-EED
AZD9291
miR-34a
non-canonical base pairing
GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH
期刊论文
OAI收割
ONCOGENE, 2019, 卷号: 38, 期号: 46, 页码: 7133-7145
作者:
Yang, Rui
;
Liu, Na
;
Chen, Ling
;
Jiang, Yiqun
;
Shi, Ying
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1457-1465
作者:
Shi, Yi
;
Ma, Hong-lei
;
Zhuang, You-wen
;
Wang, Xiao-xi
;
Jiang, Yi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
PRC2
C10ORF12
H3K27me3
histone methyltransferase
epigenetic regulation
histone modification
Metabolic regulation of gene expression by histone lactylation
期刊论文
OAI收割
NATURE, 2019, 卷号: 574, 期号: 7779, 页码: 575-+
作者:
Zhang, Di
;
Tang, Zhanyun
;
Huang, He
;
Zhou, Guolin
;
Cui, Chang
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Parental Exposure to Perfluorobutanesulfonate Impairs Offspring Development through Inheritance of Paternal Methylome
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 卷号: 53, 期号: 20, 页码: 12018-12025
作者:
Chen, Lianguo
;
Tsui, Mirabelle M. P.
;
Hu, Chenyan
;
Wan, Teng
  |  
收藏
  |  
浏览/下载:178/0
  |  
提交时间:2019/11/29
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190
作者:
Liu, Ruiqi
;
Zhang, Zhuqing
;
Yang, Hong
;
Zhou, Kaixin
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
p300 inhibitors
Epigenetics
Structure-activity relationship
Sensitive tumor cell proliferation
C646
A central role for MeCP2 in the epigenetic repression of miR-200c during epithelial-to-mesenchymal transition of glioma
期刊论文
OAI收割
Journal of Experimental & Clinical Cancer Research, 2019, 卷号: 38
作者:
Bian,Erbao
;
Chen,Xueran
;
Xu,Yadi
;
Ji,Xinghu
;
Cheng,Meng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/10/21
Glioma
MeCP2
miR-200c
SUV39H1
Hierarchical graphical model reveals HFR1 bridging circadian rhythm and flower development in Arabidopsis thaliana
期刊论文
OAI收割
NPJ SYSTEMS BIOLOGY AND APPLICATIONS, 2019, 卷号: 5, 页码: 11
作者:
Duren, Zhana
;
Wang, Yaling
;
Wang, Jiguang
;
Zhao, Xing-Ming
;
Lv, Le
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/05/24