中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [49]
采集方式
OAI收割 [49]
内容类型
期刊论文 [49]
发表日期
2022 [2]
2020 [2]
2019 [3]
2018 [2]
2017 [2]
2016 [6]
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Biochemist... [2]
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专题:上海药物研究所
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Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain
期刊论文
OAI收割
FEBS OPEN BIO, 2022, 卷号: 12, 期号: 9, 页码: 1644-1656
作者:
Liu, Xin-Yuan
;
Chen, Yi-Li
;
Liu, Guo-Jian
;
Deng, Xiang-Nan
;
Cui, Yue
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/09/30
ADCC
affinity maturation
antibody engineering
anti-GD2 antibodies
engineered Fc domain
humanized
Tyrphostin A9 protects axons in experimental autoimmune encephalomyelitis through activation of ERKs
期刊论文
OAI收割
LIFE SCIENCES, 2022, 卷号: 294, 页码: 12
作者:
Dai, Xiaodong
;
Wang, Yongmei
;
Li, Yuexin
;
Zhong, Yongping
;
Pei, Min
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15
Multiple sclerosis (MS)
Experimental autoimmune encephalomyelitis (EAE)
Extracellular signal-regulated kinase
Tyrphostin A9
Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149
作者:
Pan, Lijia
;
Nie, Litong
;
Yao, Sheng
;
Bi, Aiwei
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
neuroblastoma
bufalin
chemical proteomics
ETC
mitochondria
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tao, Ling-xue
;
Ji, Sha-sha
;
Szaloki, Dora
;
Kovacs, Tibor
;
Mandi, Attila
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
neurodegeneration
oxidative stress
apoptosis
MAPK pathway
PI3K
Akt pathway
SH-SY5Y neuroblastoma cells
Metabolic Evaluation of MYCN-Amplified Neuroblastoma by 4-[F-18]FGln PET Imaging
期刊论文
OAI收割
MOLECULAR IMAGING AND BIOLOGY, 2019, 卷号: 21, 期号: 6, 页码: 1117-1126
作者:
Li, Chao
;
Huang, Shuo
;
Guo, Jun
;
Wang, Cheng
;
Huang, Zhichao
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Glutamine
PET
MYCN
ASCT2
Neuroblastoma
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
期刊论文
OAI收割
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Wang, Yin-Yin
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
selective BChE inhibitor
virtual screening
structural optimization
molecular dynamics
anti-A beta aggregation
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
HPLC-ECD and TDDFT-ECD study of hexahydropyrrolo[1,2-a]quinoline derivatives
期刊论文
OAI收割
CHIRALITY, 2018, 卷号: 30, 期号: 7, 页码: 866-874
作者:
Toth, Laszlo
;
Mandi, Attila
;
Varadi, Daniel
;
Kovacs, Tibor
;
Szabados, Anna
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
[1,5]-hydride shift
C-H activation
density functional theory
relative and absolute configuration
Axl inhibitor R428 induces apoptosis of cancer cells by blocking lysosomal acidification and recycling independent of Axl inhibition
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2018, 卷号: 8, 期号: 8, 页码: 1466-+
作者:
Chen, Fangfang
;
Song, Qiaoling
;
Yu, Qiang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
R428
Axl
cancer cells
apoptosis
autophagy
vacuolization
Dual anti-ischemic effects of rosmarinic acid n-butyl ester via alleviation of DAPK-p53-mediated neuronal damage and microglial inflammation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 459-468
作者:
Wu, Lei
;
Wang, Hong-min
;
Li, Jin-long
;
Feng, Hong-xuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
cerebral ischemia
rosmarinic acid n-butyl ester
SH-SY5Y neuroblastoma cells
apoptosis
death-associated protein kinase
p53
microglia
inflammation