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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
采集方式
OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2023 [1]
2022 [1]
2020 [2]
2017 [3]
2015 [2]
2014 [3]
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专题:上海药物研究所
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Chemical Inhibitors Targeting the Oncogenic m
6
A Modifying Proteins
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022
作者:
Huang, Yue
;
Xia, Wenyang
;
Dong, Ze
;
Yang, Cai-Guang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14
作者:
Xiao, Senhao
;
Guo, Siqi
;
Han, Jie
;
Sun, Yanli
;
Wang, Mingchen
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Antibody-free enzyme-assisted chemical approach for detection of N-6-methyladenosine
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2020, 页码: 12
作者:
Wang, Ye
;
Xiao, Yu
;
Dong, Shunqing
;
Yu, Qiong
;
Jia, Guifang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270
作者:
Zhang, Wei-yao
;
Lu, Wen-chao
;
Jiang, Hao
;
Lv, Zheng-bing
;
Xie, Yi-qian
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
epigenetics
molecular docking
PRMT1
scaffold hopping
small-molecule inhibitor
Structural Characterization of Mannoglucan from Dendrobium nobile Lindl and the Neuritogenesis-Induced Effect of Its Acetylated Derivative on PC-12 Cells
期刊论文
OAI收割
POLYMERS, 2017, 卷号: 9, 期号: 9
作者:
Jin, Can
;
Du, Zhenyun
;
Lin, Liyan
;
Zhou, Lishuang
;
Li, Saijuan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
mannoglucan
polysaccharide
Dendrobium nobile Lindl
neuritogenesis
neurodegeneration disease
m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
期刊论文
OAI收割
CELL REPORTS, 2017, 卷号: 18, 期号: 11, 页码: 2622-2634
作者:
Cui, Qi
;
Shi, Hailing
;
Ye, Peng
;
Li, Li
;
Qu, Qiuhao
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 卷号: 137, 期号: 43, 页码: 13736-13739
作者:
Wang, Tianlu
;
Hong, Tingting
;
Huang, Yue
;
Su, Haomiao
;
Wu, Fan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal FarnesoidX Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism
期刊论文
OAI收割
CHEMMEDCHEM, 2015, 卷号: 10, 期号: 7, 页码: 1184-1199
作者:
Huang, Huang
;
Si, Pei
;
Wang, Lei
;
Xu, Yong
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
antagonists
mechanism of action
molecular dynamics
nonsteroidal ligands
receptors
Development of beta-amino-carbonyl compounds as androgen receptor antagonists
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 664-673
作者:
Zhang, Zhi-yun
;
Zhu, Yan-hui
;
Zhou, Cai-hong
;
Liu, Qing
;
Lu, Hui-li
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
prostate cancer
structural modification
androgen receptor
antagonist
molecular docking
beta-amino-carbonyl compound