机构

• 上海药物研究所 [20]
• 广州生物医药与健康研... [2]
• 上海生物化学与细胞生... [1]
• 生态环境研究中心 [1]

采集方式

• OAI收割 [24]

内容类型

• 期刊论文 [24]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [1]
• 2021 [1]
• 2020 [2]
• 2019 [1]
• 更多

学科主题

• Pharmacolo... [2]
• Biochemist... [1]

筛选

浏览/检索结果: 共24条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20 作者:  Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/06 CB2R agonist  5-HT1AR agonist  CB1R antagonist  Antidepressant  Anxiolytic   Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958 作者:  Ge, Haixia;  Ji, Beihong;  Fang, Jiahui;  Wang, Jiayang;  Li, Jing   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 function-based ligand design  receptor-ligandbinding profile  CB1/CB2  structure-activityrelationship   Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18 作者:  Lu, Lixue;  Chen, Song;  Yu, Mingcheng;  Zhou, Ronghui;  Guo, Siqi   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 ROR gamma t  Triazines  Inverse agonist  Psoriasis  Autoimmune diseases   Advances in Medicinal Chemistry of Estrogen-related Receptor Alpha (ERRa) Inverse Agonists 期刊论文  OAI收割 CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 20, 页码: 1952-1963 作者:  Zhang, Haibin;  Du, Yongli;  Zheng, Yong;  Lv, Huiting;  Yan, Zhijia   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/10/17 ERRalpha  ERRalpha inverse agonists  Breast cancer  TNBC  Signaling pathways  Inverse agonistic activity   The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134 作者:  Gao, Zhipei;  Wang, Tianxiao;  Li, Rui;  Du, Yongli;  Lv, Han   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/01/18 ERR alpha  TNBC  p-Nitrobenzenesulfonamide  inverse agonist   Molecular Dynamics Simulations Based on 1-Phenyl-4-Benzoyl-1-Hydro-Triazole ERR alpha Inverse Agonists 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 7, 页码: 14 作者:  Gao, Zhipei;  Du, Yongli;  Sheng, Xiehuang;  Shen, Jingkang   |  收藏  |  浏览/下载：13/0  |  提交时间：2021/05/24 ERRα  inverse agonists  1-phenyl-4-benzoyl-1-hydro-triazole  MD simulations   Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan   |  收藏  |  浏览/下载：92/0  |  提交时间：2020/12/24 RORγ  t  cocrystal structures  MD simulation  “  short”  inverse agonists  agonists  “  long”  inverse agonists   Cryo-EM Structure of the Human Cannabinoid Receptor CB2-G(i) Signaling Complex 期刊论文  OAI收割 CELL, 2020, 卷号: 180, 期号: 4, 页码: 645-+ 作者:  Xing, Changrui;  Zhuang, Youwen;  Xu, Ting-Hai;  Feng, Zhiwei;  Zhou, X. Edward   |  收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 Designing of novel ERR gamma inverse agonists by molecular modeling studies of docking and 3D-QSAR on hydroxytamoxifen derivatives 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 10, 页码: 1661-1673 作者:  Li, Rui;  Du, Yongli;  Shen, Jingkang   |  收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01 ERR gamma inverse agonist  Molecular docking  3D-QSAR  CoMFA  CoMSIA   A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414 作者:  Wang, Yibing;  Liu, Hong   |  收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08