中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [50]
采集方式
OAI收割 [50]
内容类型
期刊论文 [50]
发表日期
2023 [4]
2022 [6]
2021 [7]
2020 [5]
2019 [1]
2018 [5]
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Pharmacolo... [1]
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专题:上海药物研究所
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Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11
作者:
Ye, Yaqing
;
Xue, Mingzhen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Anemoside B4
Pulsatilla chinensis
metabolite identification
Pharmacokinetics
Rectal suppository
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 6, 页码: 1122-1134
作者:
Wang, Qing
;
Yao, Sheng
;
Yang, Ze-xian
;
Zhou, Chen
;
Zhang, Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
Parkinson's disease
alpha-synuclein aggregation
protein-protein interaction
03A10
MPTP/p model
enema inoculation model
Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model
期刊论文
OAI收割
FEBS JOURNAL, 2023, 页码: 19
作者:
Yang, Chuanyan
;
Tian, Fuyun
;
Hu, Mei
;
Kang, Chunlan
;
Ping, Meixuan
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
glycocalyx
H+ leak
lysosome acidification
proton channel
TMEM175
Molecular and Cellular Mechanisms of Neuropathic Pain in Aging
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 10, 页码: 1701-1716
作者:
Huang, Han
;
Wu, Jianwei
;
Chang, Yi
;
Wang, Hongwei
;
Tian, Ye
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
neuropathic pain
aging
intracellular calciumconcentration
oxidative stress
brain function
descending inhibition
innate immune cell population
central nervous system
comorbidity
Interfacial structures and decomposition reactions of hybrid anion-based ionic liquids at lithium metal surface from first-principles and ab initio molecular dynamics
期刊论文
OAI收割
JOURNAL OF MOLECULAR LIQUIDS, 2022, 卷号: 366, 页码: 11
作者:
Lu, Yunxiang
;
Tian, Ye
;
Xu, Zhijian
;
Liu, Honglai
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/11/11
Ionic liquids
Hybrid anions
SEI
Interfacial
Decomposition
Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12
作者:
Lu, Haibo
;
Lu, Tian
;
Zu, Shijia
;
Duan, Zhe
;
Guang, Yiman
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
CECR2 bromodomain
BPTF bromodomain
Small-molecule inhibitor
SAR study
Chemical probe
Identification of oleoylethanolamide as an endogenous ligand for HIF-3 alpha
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 12
作者:
Diao, Xiaotong
;
Ye, Fei
;
Zhang, Meina
;
Ren, Xintong
;
Tian, Xiaoxu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/08/16
Intestinal Glucuronidation, Prior to Hepatic Glucuronidation, Plays an Important Role in the Low Circulating Levels of Calycosin
期刊论文
OAI收割
SEPARATIONS, 2022, 卷号: 9, 期号: 5, 页码: 15
作者:
Jiang, Haodong
;
Liu, Huan
;
Hu, Pei
;
Chen, Shuoji
;
Ye, Yaqing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
calycosin
first-pass effect
intestinal glucuronidation
liver distribution
metabolism
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:
Qian, Hong-jie
;
Wang, Yu
;
Zhang, Meng-qi
;
Xie, Yuan-chao
;
Wu, Qing-qing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
VV116
nucleoside analog
SARS-CoV-2
safety
pharmacokinetics
healthy subjects
Characterization of a small-molecule inhibitor targeting NEMO/IKK beta to suppress colorectal cancer growth
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 卷号: 7, 期号: 1, 页码: 13
作者:
Yu, Zhenlong
;
Gao, Jian
;
Zhang, Xiaolei
;
Peng, Yulin
;
Wei, Wenlong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15