中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2021 [12]
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发表日期:2021
专题:上海药物研究所
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FPS-ZM1 inhibits LPS-induced microglial inflammation by suppressing JAK/STAT signaling pathway
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 100, 页码: 12
作者:
Wang, Lan
;
Zhao, Danfeng
;
Wang, Huan
;
Wang, Lele
;
Liu, Xiaohui
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/12/01
Inflammation
Microglia
LPS
RNA-seq
JAK
STAT signaling pathway
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:
Zhou, Xian
;
Feng, Xuexin
;
Wang, Dachi
;
Chen, Deheng
;
Wu, Gaoxing
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/08/17
Chaetominine
Cellular growth inhibition
Cancer cell line
Covalent warhead
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
;
Li, Yong
;
Lu, Wenchao
;
Spitters, Twgm
;
Fang, Xueyu
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
Metal-drug nanoparticles
Orthotopic osteosarcoma
Osteolytic microenvironment
Zoledronate
Radiotherapy
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Ren, Peng-xuan
;
Shang, Wei-juan
;
Yin, Wan-chao
;
Ge, Huan
;
Wang, Lin
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/06/11
SARS-CoV-2 inhibitors
RdRp
host ribosome
Virus RNA
Uncommon Bis-quinolizidine Alkaloids from the Hainan Sponge Neopetrosia chaliniformis
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 7, 页码: 1838-1842
作者:
Chen, Bao
;
Huan, Xia-Juan
;
Miao, Ze-Hong
;
de Voogd, Nicole J.
;
Gu, Yu-Cheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/21
Sponge
Neopetrosia chaliniformis
Alkaloids
Configuration determination
Cytotoxicity
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14
作者:
Wu, Qian
;
Chen, Dan-Qi
;
Sun, Lin
;
Huan, Xia-Juan
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/05/24
N2817
Bivalent BET inhibitors
Monovalent BET inhibitors
TAF1
Anticancer activity
Polyoxygenated Cembranoids from Soft Coral Lobophytum Crassum and Their Anti-tumoral Activities
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 3, 页码: 640-646
作者:
Yin, Fang-Zhou
;
Huan, Xia-Juan
;
Mudianta, I. Wayan
;
Miao, Ze-Hong
;
Wang, Hong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Soft coral
Lobophytum crassum
Cembranoids
Anti‐
tumoral activity
Stereochemistry
Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 33, 页码: 127749
作者:
Yang, Bowen
;
Wu, Qian
;
Huan, Xiajuan
;
Wang, Yingqing
;
Sun, Yin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/21
TNIK inhibitor
1H-pyrrolo[2,3-b]pyridine
IL-2 secretion inhibitory