机构

• 上海药物研究所 [40]

采集方式

• OAI收割 [40]

内容类型

• 期刊论文 [40]

发表日期

• 2023 [40]

学科主题

筛选

浏览/检索结果: 共40条，第1-10条 帮助 限定条件 发表日期：2023    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids 期刊论文  OAI收割 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2023, 卷号: 185, 页码: 13-25 作者:  Zhao, Chengcheng;  Jiang, Xiangrui;  Peng, Liyuan;  Zhang, Yan;  Li, Huihui   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/01/16 Heart failure  Hypertrophy  Epoxyeicosatrienoic acids  Soluble epoxide hydrolase   High-throughput design of energetic molecules 期刊论文  OAI收割 JOURNAL OF MATERIALS CHEMISTRY A, 2023, 卷号: 11, 期号: 45, 页码: 25031-25044 作者:  Liu, Jian;  Zhao, Shicao;  Duan, Bowen;  He, Xudong;  Yang, Chunming   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/19 Identification of a carbohydrate recognition motif of purinergic receptors 期刊论文  OAI收割 ELIFE, 2023, 卷号: 12, 页码: 17 作者:  Zhao, Lifen;  Wei, Fangyu;  He, Xinheng;  Dai, Antao;  Yang, Dehua   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/19 G-protein coupled receptor  sugar nucleotide  recogonition mechanism  functional motif  Human   Ligand activation mechanisms of human KCNQ2 channel 期刊论文  OAI收割 Nature communications, 2023, 卷号: 14, 期号: 1, 页码: 6632 作者:  Ma, Demin;  Zheng, Yueming;  Li, Xiaoxiao;  Zhou, Xiaoyu;  Yang, Zhenni   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/26 Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane 期刊论文  OAI收割 PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14 作者:  Chen, Xi;  Yang, Jia-bin;  Cao, Hui-hui;  Fang, Xiao-chuan;  Liu, Shan-hong   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Liang-Ge-San  Dengue virus serotype 2  Heat shock protein 70  Caveolin1  Envelope protein   Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12 作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/02/27 O-GlcNAcylation  O-GlcNAc transferase  High-throughput screening  Inhibitor   Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303 作者:  Xiang, Weiguo;  Zhao, Lijie;  Han, Xin   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08