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• 上海药物研究所 [153]
• 昆明植物研究所 [17]
• 过程工程研究所 [16]
• 西北高原生物研究所 [10]
• 自动化研究所 [8]
• 高能物理研究所 [6]
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• OAI收割 [240]
• iSwitch采集 [6]

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• 期刊论文 [234]
• 学位论文 [12]

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• 2024 [2]
• 2023 [9]
• 2022 [23]
• 2021 [17]
• 2020 [28]
• 2019 [24]
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学科主题

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浏览/检索结果: 共246条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Worm-like micelles facilitate the intestinal mucus diffusion and drug accumulation for enhancing colorectal cancer therapy 期刊论文  OAI收割 Chinese Chemical Letters, 2024, 卷号: 35, 期号: 6, 页码: 108967 作者:  Zhou, Yihan;  Gao, Duo;  Wang, Yaying;  Liang, Li;  Zhang, Qingyu   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/26 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/04/09 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19 From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18 作者:  Chen, Yi;  Liu, Qiu-pei;  Xie, Hua;  Ding, Jian   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/01/16 KRAS mutation  KRAS(G12C) inhibitor  Pan-KRAS inhibitor  SHP2 allosteric inhibitor  SOS1 inhibitor  combination therapy   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells 期刊论文  OAI收割 LIFE SCIENCES, 2023, 卷号: 332, 页码: 10 作者:  Su, Ai-Ling;  Tian, Chang-Qing;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 CD73  Proteasome inhibitors  ERK  NSCLC   Development of HSP90 inhibitors-SN38 conjugates for cancer treatment 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 11 作者:  Cao, Yuting;  Shen, Qianqian;  Ding, Mengyuan;  Chen, Yi;  Lu, Wei   |  收藏  |  浏览/下载：64/0  |  提交时间：2023/10/17 HSP90  SN38 conjugate  Drug accumulation  Cancer treatment   Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9 作者:  Li, Hua-ying;  Chen, Yi-li;  Deng, Xiang-nan;  Li, Huan-huan;  Tan, Jie   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 cancer immunotherapy  B7-H3  PD-L1  bispecific antibodies  VHH  antibody-dependent cell-mediated cytotoxicity (ADCC)   Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11 作者:  Wang, Han-lin;  Li, Jia-nan;  Kan, Wei-juan;  Xu, Gao-ya;  Luo, Guang-hao   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 acute myeloid leukemia  cytarabine  daunorubicin  idarubicin  drug resistant  multi-omics  autophagy  chloroquine phosphate   Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037 作者:  Li, Daqiang;  Zhang, Zhuo;  Li, Yalei;  Wang, Xinyi;  Zhong, Hanyue   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17