中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2022 [11]
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专题:上海药物研究所
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发表日期:2022
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Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Shi, Wei
;
Zhang, Jianxin
;
Liu, Liya
;
Li, Wanzhen
;
Liu, Zhi
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Qi, Wei-liang
;
Li, Hui-yu
;
Wang, Yi
;
Xu, Lan
;
Deng, Jie-ting
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
AMG510
KRas(G12C)
PI3K
drug resistance
combination therapy
Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice
期刊论文
OAI收割
FASEB JOURNAL, 2022, 卷号: 36, 期号: 9, 页码: 14
作者:
Yan, Fang-Zhi
;
Qian, Hui
;
Liu, Fang
;
Ding, Chen-Hong
;
Liu, Shu-Qing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/09/30
hepatic stellate cell
inflammation
inhibitor
liver fibrosis
protein arginine methyltransferase 1
Sugar-Derived Isotropic Nanoscale Polycrystalline Graphite Capable of Considerable Plastic Deformation
期刊论文
OAI收割
ADVANCED MATERIALS, 2022, 页码: 12
作者:
Sun, Boqian
;
Chen, Daming
;
Cheng, Yuan
;
Fei, Weidong
;
Jiang, Danyu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
isotropic materials
nanostructured carbon
plasticity
polycrystalline graphite
van der Waals materials
A loosened gating mechanism of RIG-I leads to autoimmune disorders
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 10, 页码: 5850-5863
作者:
Lei, Yixuan
;
Fei, Panyu
;
Song, Bin
;
Shi, Wenjia
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/21
A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 10
作者:
Xu, Yingna
;
Feng, Wenbo
;
Zhou, Qingtong
;
Liang, Anyi
;
Li, Jie
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors
期刊论文
OAI收割
EMBO REPORTS, 2022, 页码: 17
作者:
Jiang, Zhiwu
;
Cheng, Lin
;
Wu, Zhiping
;
Zhou, Linfu
;
Wang, Haitao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
biomarkers
hepatocellular carcinoma
humanized mouse models
immunotherapy
oncogenes
Monoterpene indole alkaloids from Melodinus cochinchinensis (Lour.) Merr.
期刊论文
OAI收割
FITOTERAPIA, 2022, 卷号: 157, 页码: 4
作者:
Wang, Xiao-Feng
;
Wei, Ren-Jie
;
Fang, Qiang-Qiang
;
He, Wan-Ying
;
Jiang, Kun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/06/15
Artemisinin derivative TPN10466 suppresses immune cell migration and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis
期刊论文
OAI收割
CELLULAR IMMUNOLOGY, 2022, 卷号: 373, 页码: 10
作者:
Liu, Guangyu
;
Jiang, Xiangrui
;
Han, Mengyao
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/16
EAE
Cell migration
Th1
Th17 differentiation
Spiroarborin, an ent-Clerodane Homodimer from Callicarpa arborea as an Inhibitor of the Eleven-Nineteen Leukemia (ENL) Protein by the YEATS Domain
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2022, 卷号: 85, 期号: 2, 页码: 317-326
作者:
Pu, De-Bing
;
Guo, Si-Qi
;
Ni, Dong-Xuan
;
Lin, Jing
;
Gao, Jun-Bo
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/06/15