中国科学院机构知识库网格系统: 检索

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	Targeting ST8SIA6-AS1 counteracts KRAS^G12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文 OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22 作者: Wang, Yafang; Yao, Mingyue; Li, Cheng; Yang, Kexin; Qin, Xiaolong \| 收藏 \| 浏览/下载：7/0 \| 提交时间：2024/01/26 KRAS(G12C) c-Myc PLK1 LncRNA ST8SIA6-AS1 Drug resistance
	Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead 期刊论文 OAI收割 GENES & DISEASES, 2023, 卷号: 10, 期号: 2, 页码: 403-414 作者: Li, Hui-yu; Qi, Wei-liang; Wang, Yu-xiang; Meng, Ling-hua \| 收藏 \| 浏览/下载：117/0 \| 提交时间：2023/10/17 Biomarkers Covalent KRasG12Cinhibitors Drug resistance Human cancers KRASG12Cmutation
	Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R 期刊论文 OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12 作者: Qi, Wei-liang; Li, Hui-yu; Wang, Yi \| 收藏 \| 浏览/下载：15/0 \| 提交时间：2023/04/10 AMG510 KRas(G12C) PI3K drug resistance combination therapy
	KRAS-Mutant Non-Small Cell Lung Cancer: An Emerging Promisingly Treatable Subgroup 期刊论文 OAI收割 FRONTIERS IN ONCOLOGY, 2021, 卷号: 11 作者: Xie, Mingying; Xu, Xiaoling; Fan, Yun \| 收藏 \| 浏览/下载：36/0 \| 提交时间：2021/06/15 KRAS-mutant NSCLC targeted therapy immunotherapy AMG510 MRTX849
	Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17 作者: Xiao, Xuanzheng; Lai, Mengzhen; Song, Zilan; Geng, Meiyu; Ding, Jian \| 收藏 \| 浏览/下载：26/0 \| 提交时间：2021/05/24 KRAS Covalent inhibitor Pyridopyrimidinone Antiproliferative effect Scaffold hopping